The Hemodynamics of Hypertension and Anti Hypertensive Therapy

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Ablad, B. , and Johnsson, G. : Comparative effects of intra-arterially administered hydralazine and sodium nitrate on blood flow and volume of forearm. Acta pharmacol et toxical., 20: 1, 1963.

Ablad, B. : A study of the mechanism of the hemodynamic effects of hydralazine in man . Acta pharmacol et toxicol., 20: 1, 1963.

Tangri, K.K. , and Bhargava, K.P. : The central hypotensive action of 1-hydrazinophthalazine (C-5968). Arch. internat. pharmacodyn., 125: 331, 1960 .

Moyer, J.H. , Handley, C.A. , and Huggins, R.A. : Some pharmacodynamic effects of 1-hydrazinophthalazine (C-5968) with particular reference to renal function and cardiovascular response . J. Pharmacol. & Exper. Therap., 103: 368, 1951 .

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Gorlin, R. , Brachfeld, N. , MacLeod, C. , and Bopp, P. : Effect of nitroglycerin on the coronary circulation in patients with coronary artery disease or increased left ventricular work. Circulation , 19: 705, 1959.

Napodano, R.J. , Caliva, F.S. , and Lyons, R.H. : Digital hemodynamics in hypertension and a possible mechanism of action of the benzothiadiazine diuretics. Clin. Res., 10: 178,1962.

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Freed, S.C. : Mechanism of anti-hypertensive action of quinethazone. Proc. Soc. Exper. Biol. & Med., 114: 421, 1963 .

Conway, J. , and Lauwers, P. : Hemodynamic and hypotensive effects of long-term therapy with hydrochlorothiazide . Circulation, 21: 21, 1960.

Conway, J. , and Lauwers, P. : The hypotensive and hemodynamic effects of chlorothiazide. In: Hypertension, Recent Advances, ed. by A. N. Brest and J. H. Moyer , p. 256, Lea and Febiger, Philadelphia, 1961 .

Cannon, P.J. , Whitlock, R.T. , Morris, R.C. , Angers, M. , and Laragh, J.H. : Effect of alpha-methyldopa in severe and malignant hypertension. J. A. M. A., 179: 673, 1962.

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Assali, N.S. , Baird, W.W. , Douglass, R.A. , and Tioseco, E.L. : Hemodynamic effects of a hydrazinophthalazine compound (Apresoline) in hypertensive complications of pregnancy. Am. J. Med., 14: 491, 1953.

Freis, E.D. , Rose, J.C. , Higgins, T.F. , Finnerty, F.A. , Jr., Kelley, R.T. , and Partenope , E.A. : The hemodynamic effects of hypotensive drugs in man. IV. 1-Hydrazinophthalazine. Circulation, 8: 199, 1953.

Wilkinson, E.L. , Backman, H. , and Hecht, H.H. : Cardiovascular and renal adjustments to a hypotensive agent (1-hydrazinophthalazine: CIBA BA-5968: Apresoline). J. Clin. Invest., 31: 872, 1952.

Rowe, G.G. , Huston, J.H. , Maxwell, G.M. , Crosley, A.P. , Jr., and Crumpton , C.W. : Hemodynamic effects of 1-hydrazinophthalazine in patients with arterial hypertension. J. Clin. Invest., 34: 115, 1955.

Rowe, G.G. , Huston, J.H. , Maxwell, G.M. , Weinstein, A.B. , Tuchman, I.I. , and Crumpton , C.W. : The effects of 1-hydrazinophthalazine upon coronary hemodynamics and myocardial oxygen metabolism in essential hypertension . J. Clin. Invest., 34: 696, 1955.

Rowe, G.G. , Chelius, C.J. , Afonso, S. , Gurtner, H.P. , and Crumpton , C.W. : Systemic and coronary hemodynamic effects of erythrol tetranitrate. J. Clin. Invest. , 40: 1217, 1961.

Afonso, S. , Rowe, G.G. , Lowe, W.C. , and Crumpton, C.W. : Systemic and coronary hemodynamic effects of isosorbide dinitrate. Am. J. M. Sc. 246: 584, 1963.

Dresdale, D.T. , Yuceoglu, Y.Z. , Reyes, A. , Jr., Lunger, M. , and Nassar, A.M. : Hemodynamic effects of isosorbide dinitrate in patients with rheumatic heart disease and pulmonary hypertension. Angiology, 14: 349, 1963.

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Varnauskas, E. , Cramer, G. , Malmcrona, R. , and Werkö, L. : Effect of chlorothiazide on blood pressure and blood flow at rest and on exercise in patients with arterial hypertension . Clin. Sc., 20: 407, 1961.

Villarreal, H. , Revollo, A. , Exaire, J.E. , and Larrondo , F. : Effect of chlorothiazide on renal hemodynamics. Circulation, 26: 409, 1962.

Rowe, G.G. , Castillo, C.A. , Crosley, A.P. , Jr., Maxwell , G.M. , and Crumpton, C.W. : Acute systemic and coronary hemodynamic effects of chlorothiazide in subjects with systemic arterial hypertension. Am. J. Cardiol., 10: 183, 1962.

Conway, J. , Keitzer, F. , and Miller, J.D. : Hemodynamic effects of a sodium-retaining thiazide derivative: Preliminary observations. J. Lab. & Clin. Med., 58: 809, 1961.

Rowe, G.G. , Leicht, T.R. , Boake, W.C. , Kyle, J.C. , and Crumpton , C.W. : The systemic and coronary hemodynamic effects of diazoxide. Am. Heart J., 66: 636, 1963.

Wolfer, H.J. , Schneider, K.W. , and Hochrein , H. : Klinische und hämodynamische Untersuchungen über eine neue antihypertensive substanz aus der thiazidreihe ohne diuretische Wirkung. Arzneimittel-Forsch., 13: 748, 1963.

Kakaviatos, N. , Tuckman, J. , and Finnerty, F.A. , Jr.: An antihypertensive agent which reduces peripheral resistance. Clin. Res., 10: 174, 1962.

Wilson, W.R. , and Okun, R. : The acute hemodynamic effects of diazoxide in man. Clin. Res., 10: 184, 1962.

Wilson, W.R. , and Okun, R. : The acute hemodynamic effects of diazoxide in man. Circulation, 28: 89, 1963.

Freis, E.D. : Observations of cardiac output, peripheral blood flow and blood volume in hypertension—before and during treatment. In: Hypertension , ed. by J. H. Moyer , p. 123, W. B. Saunders Co., Philadelphia, 1959.

Dollery, C.T. , Emslie-Smith, D. , and Shillingford , J.P. : Haemodynamic effects of guanethidine. Lancet, 2: 331, 1961.

Braunwald, E. , Ross, J. , Jr., Kohler, R.L. , Gaffney, T.E. , Goldblatt, A. , and Mason, D.T. : Reflex control of the systemic venous bed . Circulation Res., 12: 539, 1963.

Reynolds, T.B. , Paton, A. , Freeman, M. , Howard, F. , and Sherlock, S. : The effect of hexamethonium bromide on splanchnic blood flow, oxygen consumption and glucose output in man. J. Clin. Invest., 32: 793, 1953.

McKenna, D.H. , Afonso, S. , and Rowe, G.G. : Systemic and coronary hemodynamic effects of pargyline hydrochloride (MO 911) an amine oxidase inhibitor. Fed. Proc., 23: 230, 1964.

Rowe, G.G. , Afonso, S. , Lugo, J.E. , and Crumpton, C.W. : Antianginal effects of monoamine oxidase inhibitors. In: Cardiovascular Drug Therapy, ed. by A. N. Brest and J. H. Moyer , p. 297, Grune and Stratton, New York, 1965 .

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