Pharmacodynamics of Parenteral and Oral Anticoagulants

Jorpes, J.E. : Heparin in the Treatment of Thrombosis, Ed. 2. Oxford University Press, London, 1946.

Wright, I.S. : The pathogenesis and treatment of thrombosis with a clinical and laboratory guide to anticoagulant therapy. In Modern Medical Monographs . Grune & Stratton, Inc., New York, 1952.

Koller, T., AND Merz, W. R. (Editors): Thrombosis and Embolism: Proceedings of the First International Conference. Benno Schwabe & Co., Basel, 1954.

Alexander, B. , AND Wessler, S. : A guide to anticoagulant therapy. Circulation, 24: 123, 1961.

Pickering, G. W. (Editor): Symposium on Anticoagulant Therapy. Harvey & Blythe, Ltd., London, 1961.

Alexander, B. : Anticoagulant therapy with coumarin congeners. Action and guide lines. Am. J. Med., 33: 679, 1962.

Jorpes, J.E. : Heparin, its chemistry, pharmacology and clinical use. Am. J. Med., 33: 692, 1962.

Engelberg, H. : Heparin. Charles C Thomas , Springfield, III., 1962.

Douglas, A.S. : Anticoagulant Therapy. Blackwell Scientific Publications, Oxford, 1962.

Owren, P.A. : Indications for anticoagulant therapy. New England J. Med., 268: 1173 and 1228, 1963.

Jorpes, J.E. , Boström, H. , AND Mutt, V. : The linkage of the amino group in heparin . J. Biol. Chem., 183: 607, 1950.

Detakats, G. : The subcutaneous use of heparin. A summary of observations. Circulation, 2: 837, 1950.

Engelberg, H. : Prolonged anticoagulant therapy with subcutaneously administered concentrated aqueous heparin. Surgery, 36: 762, 1954.

Bauer, G. , Kallner, S. , Jorpes, J.E. , AND Boström, H. : Intramuscular administration of heparin. Acta med. scandinav. , 136: 188, 1950.

Bauer, G. : Nine years' experience with heparin in acute venous thrombosis. Angiology, 1: 161, 1950.

Warren, R. , AND Belko, S. : A comparison of heparin and bishydroxycoumarin (Dicumarol) as anticoagulants . Arch. Surg., 74: 50, 1957.

Carey, L.C. , AND Williams, R.D. : Comparative effects of dicoumarol, Tromexan and heparin on thrombus propagation. Ann. Surg., 152: 919, 1960.

Williams, R.D. , AND Carey, L.C. : Studies in production of "Standard" venous thrombosis. Ann. Surg., 149: 381, 1959.

Bauer, G. : Thirteen years' experience of heparin therapy. In Thrombosis and Embolism: First International Conference, p. 721. Benno Schwabe & Co., Basel, 1954.

Engelberg, H. : Heparin in acute myocardial infarction. California Med., 91: 327, 1959.

Griffith, G. , Zinn, W.J. , Engelberg H. , Dooley, J.V. , AND Anderson, R. Heparin vs. heparin bishydroxycoumarin therapy. J. A. M. A. , 174: 1157, 1960.

Dimond D.G. , AND Trotta P.F. : The advantages and disadvantages of using heparin as the sole anticoagulant during the first 30 days after acute myocardial infarction Dis. Chest, 40: 214, 1961.

Carleton, R.A. , AND Burack W.R. : Heparin administration after acute myocardial infarction. New England J. Med., 263: 1002, 1960 .

Schumacher, E.E. , JR., Drake, J.R. , AND Feenstra , L.H. : Heparin and the oral anticoagulants. A comparison with special reference to acute myocardial infarction . Am. J. Cardiol. 9: 568, 1962.

Hilden, T. , Iversen, R. , Raaschou, F. , AND Schwartz, M. : Anticoagulants in acute myocardial infarction. Lancet, 2: 327, 1961.

Friedberg, C.H. : Anticoagulants in acute myocardial infarction . J. A. M. A., 183: 904, 1963.

Weiner, M. , Brodie, B.B. , AND Burns, J.J. : A comparative study of hypoprothrombinemic agents: the physiologic disposition and chemical pharmacology of coumarin and indanedione compounds. In Thrombosis and Embolism: Proceedings of the First International Conference, p. 181. Benno Schwabe & Co., Basel, 1954.

Weiner, M. , Shapiro, S. , Axelrod, J. , Cooper, J.R. , AND Brodie, B.B. : The physiological disposition of Dicumarol in man. J. Pharmacol. & Exper. Therap., 99: 409, 1950.

Schulert, A.R. , AND Weiner, M. : The physiologic disposition of phenylindanedione in man. J. Pharmacol. & Exper. Therap., 110: 451, 1954.

Jaques, L.B. : The physiology of the anticoagulants. Rev. hémat., 10: 379, 1955.

O'Reilly, R.A. , Aggeler, P.M. , Hoag, M.S. , AND Leong, L. : Studies on the coumarin anticoagulant drugs. The assay of warfarin and its biological application. Thromb. Diath. Hemorrh., 8: 82, 1962.

O'Reilly, R.A. , Aggeler, P.M. , AND Gibbs, J.O. : Hemorrhagic state due to surreptitious ingestion of bishydroxycoumarin. New England J. Med., 267: 19, 1962.

Miller, G.J. , Mersereau, M.O. , Lowen-Thal, J. , AND Jaques, L.B. : Distribution of phenylindanedione in blood and tissues after oral and intravenous administration. Thromb. Diath. Haemorrh., 2: 236, 1958.

O'REILLY: Unpublished data.

Owren, P.A. : Thrombotest: new method for controlling anticoagulant therapy. Lancet. 2: 754, 1959.

Owren, P.A. : Control of anticoagulant therapy. Arch. Intern. Med., 111: 248, 1963.

Graham, J.B. : Stuart clotting defect and Stuart factor. Thromb. Diath. Haemorrh., 4: (supp.) 22, 1960.

Fremont, R.E. : Bleeding complications and coagulation factors in long term anticoagulant therapy. In Transactions VIIth International Congress Internal Medicine, Munich, Germany, Sept. 1962. Vol. 1, p. 181. G. B. Thieme, Stuttgart , 1963.

Fremont, R.E. , Wiedeman, M. , AND Lubell D. : A comparison of bishydroxycoumarin (Dicumarol) and warfarin sodium (Coumadin) in terms of coagulation factor changes and bleeding complications. Am. J. Med. Sc., 245: 265, 1963 .

Sise, H.S. , Lavelle, S.M. , Adams D. , AND Becker M. : Relations of hemorrhage and thrombosis to prothrombin during treatment with coumarin type anticoagulants. New England J. Med., 259: 266, 1958.

Fremont, R.E. , Disalvo S. , AND Branstein, M. : Comparison of the Owrens' Thrombotest with the quick one-stage and the prothrombin-proconvertin test, to be published.

Spooner, M. , AND Myer, O. 0.: The effect of dicoumarol (3,3'-methylenebis-4-hydroxy-coumarin) on platelet adhesiveness. Am. J. Physiol., 142: 279, 1944.

Weiner, M. , Zeltmacher, K. , Reich, C. , AND Shapiro, S. : Platelet adhesiveness. Blood, 3: 1275, 1948.

Wasserman, L.R. , AND Stats, D. : Clinical observations on effect of 3,3'-methylenebis-4-hydroxycoumarin . Am. J. M. Sc., 206: 466, 1943.

Gilbert, N.C. , AND Nalefski, L.A. : The effect of heparin and dicoumarol in increasing the coronary flow volume. J. Lab. & Clin. Med. , 34: 797, 1949.

Thompson, G.R. , Mikkelson, W.M. , AND Willis, P.W. : The uricosuric effect of certain oral anticoagulant drugs. J. Lab. & Clin. Med., 52: 950, 1958.

Williams, E.D. , AND Doniach, I. : The anti-thyroid activity of the anticoagulant phenylindanedione. J. Endocrinol., 21: 421, 1961.

Blumberg, H. , Dayton, H.B. , AND Gordon, S.M. : Bronchodilator action of the anticoagulant warfarin sodium. Science, 127: 188, 1958.

Fremont, R.E. , AND Jagendorf, B. : Clinical observations on use of warfarin (Coumadin) sodium, a new anticoagulant. J. A. M. A., 165: 1381, 1957.