The Safety of β-Propiolactone as a Biologic Sterilizing Agent

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Murray, R. : National Institutes of Health, Public Health Service, Bethesda, Md., Personal communication.

Murray, R. , Diefenbach, C.L. , Geller, H. , Leon, N.C. , AND Ratner, F. : The problems of reducing the danger of serum hepatitis from blood and blood products. New York State J. Med., 55: 1145, 1955 .

Logrippo, G.A. , AND Rupe, C.E. : Chemical sterilization of whole blood and plasma: beta-propiolactone . In Henry Ford Hospital Symposium: Hepatitis Frontiers, Ch. 31. Little, Brown & Company, Boston, 1957.

Hartman, F.W. , AND Logrippo, G.A. : Combined beta-propiolactone and ultraviolet irradiation for plasma sterilization . In Henry Ford Hospital Symposium: Hepatitis Frontiers, Ch. 33. Little, Brown & Company, Boston, 1957.

Kelly, A.R. , Hartman, F.W. , AND Rupe, C.E. : The toxicology of beta-propiolactone. In Henry Ford Hospital Symposium: Hepatitis Frontiers, Ch. 32. Little, Brown & Company, Boston, 1957 .

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Roe, F.J.C. , AND Salaman, M.H. : Further studies on incomplete carcinogenesis: Triethelene melamine, 1,2-benzanthracene and beta-propiolactone, as initiators of skin tumor formation in the mouse . Brit. J. Cancer, 9: 177, 1955.

Roe, F.J.C. , AND Glendenning, D.M. : The carcinogenicity of beta-propiolactone for mouse skin. Brit. J. Cancer, 10: 357, 1956.

Monto, R.W. : New approach to the thrombocytopathies (thrombocytopathy A). Fed. Proc., 17: 396, 1958.

Johnson, S.A. , AND Basinski, D.H. : Platelet factor 3 in blood coagulation . Fed. Proc., 17: 81, 1958.

Logrippo, G.A. : Sterilization of platelet factor-3 with beta-propiolactone and ultraviolet irradiation. Fed. Proc., 17: 524, 1958.

Logrippo, G.A. , Overhulse, P.R. , Szilagyi , D.E. , AND Hartman, F.W. : Procedure for sterilization of arterial homografts with beta-propiolactone. Lab. Invest., 4: 217, 1955.

Szilagyi, D.E. , Mcdonald, R.T. , Smith , R.F. , AND Whitcomb , J.G. : Biological fate of human arterial homografts. A. M. A. Arch. Surg., 75: 506, 1957.

Logrippo, G.A. , Burgress, B. , Teodora , R. , AND Fleming, F.L. : Procedure for bone sterilization with beta-propiolactone . J. Bone & Joint Surg., 39: 1356, 1957 .

Logrippo, G.A. , AND Eidam, C.R. : Sterilization and detoxification of serum for tissue culture by combined beta-propiolactone and ultraviolet irradiation . 9th Annual Meeting, Tissue Culture Association , Philadelphia, 1958.

Logrippo, G.A. : The hazards in the use of serum for tissue culture media. Univ. Michigan M. Bull., 24: 191, 1958.