The Postphlebitic Syndrome: Discussion of Surgical Treatment

Edwards, E.A. : The treatment of varicose veins, anatomical factors of ligation of the great saphenous vein. Surg., Gynec. & Obst., 59: 916, 1934.

Moore, W. : The operative treatment of varicose veins, etc., inter-colon. M. J. Australia, 1: 393, 1896.

Schiassi, B. : La cure des varices du membre inferieur, par l'injection intraveineuse d'une solution d'iode. Semaine méd. Par., 28: 601, 1908.

Homans, J. : The operative treatment of varicose veins and ulcers, based upon a classification of these lesions. Surg., Gynec. & Obst., 22: 143, 1916.

De Takats, G. : Ambulatory ligation of the saphenous vein. J.A.M.A., 94: 1194, 1930.

Homans, J. : The late results of femoral thrombophlebitis and their treatment. New England J. Med. 235: 249, 1946.

Linton, R.R. AND Hardy, I.B. , JR.: Post-thrombotic sequelae of the lower extremities. Treatment by superficial femoral vein interruption and stripping of the saphenous veins (A preliminary report). S. Clin. N.A. , 27: 1171, 1947.

Vaughn, A.M. , Annan, C.M. AND Caserta, J.A. : Treatment of varicose veins. S. Clin. N.A., 32: 287, 1952.

Leriche, R. AND Kunlin, J. : Traitement immédiat des phlébites post-opératoires par l'infiltration novocainique du sympathique lombaire. Presse méd., 42: 1481. 1934 .

Ochsner, A. AND Debakey, M. : Treatment of thrombophlebitis by novacain block of sympathetics: technique of injection. Surgery, 5: 491, 1939.

Leriche, R. : Removal of the superior lumbar ganglion in painful sequelae of phlebitis of the lower extremity, Schweiz. med. Wchnschr., 68: 451, 1938.

Considérations sur le traitement chirurgical de la phlébite du membre inferieur et de ses séquelles eloignées. J. Internat. chir., 3: 586, 1938.

Ochsner, A. AND Debakey, M. : Thrombophlebitis, role of vasospasm in production of clinical manifestations . J.A.M.A., 114: 117, 1940.

De Sousa P.A. : The innervation of the veins. Its role in pain, venospasm, and collateral circulation. Surgery, 19: 731, 1946.

Homans, J. : Exploration and division of femoral and iliac veins in the treatment of thrombophlebitis of the leg. New England J. Med., 224: 179, 1941 .

Buxton, R.W. , Farris, J.M. , Moyer, C.A. AND Coller, F.A. : Surgical treatment of longstanding deep phlebitis of the leg. Surgery, 15: 749, 1944.

— AND Coller, F.A. : Surgical treatment of longstanding deep phlebitis of the leg: II. A supplementary report. Surgery, 18: 663, 1945.

Linton, R.R. AND Hardy, I.B. , JR.: Postthrombotic syndrome of the lower extremity. Treatment by interruption of the superficial femoral vein and stripping of long and short saphenous veins. S. Clin. N.A., 24: 452, 1948.

Bauer, G. : The etiology of leg ulcers and their treatment by resection of the popliteal vein. J. Internat. Chir., 8: 937, 1948.

Glasser, S.T. : The basis of treatment in the postphlebitic syndrome. New York State J. Med., 49: 1923, 1949 .

Sandegård, E. : Experiences with retrograde phlebography and resection of the superficial femoral vein in post-thrombotic leg complaints . Nordisk. Med., 41: 560, 1949; in Ex. Med. 4: 115, 1950.

Walker, A.J. : Treatment of post-phlebitic leg and application of venous pressure measurement. Brit. M. J., p. 1307, 1950.

De Takats, G. AND Graupner, G.W. : Division of the popliteal vein in deep venous insufficiency of the lower extremities. Surgery, 29: 342, 1951.

De Takats, G. Quint, H. , Tillotson, R. AND Crittendon, P.J. : The impairment of the circulation in the varicose extremity. Arch. Surg., 18: 671, 1929.

Warren, R. , White, E.A. AND Belcher, C.D. : Venous pressures in the saphenous system in normal, varicose and postphlebitic extremities. Alterations following femoral vein ligation. Surgery, 26: 435, 1949.

Stürup, H. AND Højensgård, I.C. : Venous pressure in the deep veins of the lower extremity of patients with primary and post-thrombotic varicose veins, study of the statics and dynamics of the venous system of the lower extremity under pathological conditions. III Acta chir. Scand., 99: 526, 1950.

Decamp, P.T. , Schramel, R.J. , Ray, C.J. , Feiblemax, N.D. , Ward, J.A. AND Ochsxer, A. : Ambulatory venous pressure determinations in postphlebitis and related syndromes. Surgery, 29: 44, 1951.

Ward, J.A. , AND Ochsner, A. : Ambulatory venous pressure studies in postphlebitic and other disease states. Surgery, 29: 365, 1951.

Dos Santos, J.C. : La phlébographie directe: conception, technique, premiers résultats. J. Internat. Chir. T., III: 625, 669, 1938.

Berberich, J. AND Hirsch, S. : Die röntgenographische darstellung, der artonen und venen am lebenden menschen. Klin. Wchnschr., 2: 2226, 1923.

Mcpheeters, H.O. AND Rice, C.O. : Varicose veins, circulation and direction of venous flow: experimental proof. Surg., Gynec. & Obst., 49: 29, 1929.

Dougherty, J. AND Homans, J. : Venography, a clinical study. Surg., Gynec. & Obst., 71: 697, 1940.

Baker, E.C. AND Sedwitz, S.H. : Observations on venography of lower extremities. Radiology , 41: 451, 1943.

Robertson, H.R. , Share, M. AND Mcgovern, J.E. : Venographic studies in the postphlebitic limb. Int. Coll. of Surgeons, 12: 516, 1949.

Bauer, G. : Patho-physiology and treatment of the lower leg stasis syndrome. Angiology, 1: 1, 1950.

Martin, R.S. AND Mccleery, R.S. : An improved method of venography for the preoperative evaluation of the postphlebitic extremity. Surgery, 28: 322, 1950.

Servelle, M. : Étude de 420 cas de séquelles de phlébites. Sem. hôp, Paris, 26: 2483, 1950.

Frileux, C. : La maladie post-phlébitique. La France Médicale, 13: 10, 1950.

Ferreira, J.A. , Villamil, E.J.F. AND Ciruzzi , O. : Dynamic phlebography . Angiology, 2: 350, 1951.

Decamp, P.T. , Landry, R.M. , Ochsner, A. AND Debakey, M. : Spontaneous thrombophlebitis. Surgery, 31: 43, 1952.

Leonelli, U. : Le thromboflebiti da sforzo o traumatiche . Policlinico (sez. prat.), 39: 965, 1932.

Cottalorda, J. : La thrombo-phlébite par effort. Lyon. Chir., 29: 169, 1932.

Kaplan, T. : Thrombophlebitis of veins of lower extremities following effort and strain. Ind. Med., 10: 328, 1941.

Adams, J.C. : Etiological factors in varicose veins of the lower extremities. Surg., Gynec. & Obst., 69: 717, 1939.

Mccutchen, G.T. AND Cantey, W.C. : Phlebothrombosis, occurring in absence of trauma or bed rest. J. South Carolina M. A., 44: 37, 1948.

Crane, C. : Deep venous thrombosis in the leg following effort or strain. New England J. M., 246: 529, 1952.

Scott, W.J.M. : Postphlebitic and varicose venous stasis. Clinical results of treatment by pulsatile air—pressure principle. J.A.M.A., 147: 1195, 1951.

Halse, T.H. : The post-thrombotic circulatory syndrome and its surgical treatment. Lagenbeck's archiv für klinische chirurgie und dentsche zeitschrift für chirurgie. 270: 30, 1951; abstracted in International Surgical Digest, 53: 181, 1952.

Cokkinis, A.J. : Chronic ulcer of leg. Lancet , 1: 1168, 1933.

Bauer, G. : Heparin as therapeutic against thrombosis, results of one year's treatment at Mariestad hospital. Acta Chir. Scandinav., 86: 267, 1942.

Zilliacus, H. : Quoted by J. Erik Jorpes: The origin and physiology of heparin: the specific therapy in thrombosis. Ann. Int. Med., 27: 361, 1947.

Wright, A.D. : Treatment of indolent ulcer of leg. Lancet, 1: 457, 1931.

Abst., Indolent ulcers of leg. Brit. M. J., 1: 398, 1931.

Kuntz, A. : The autonomic nervous system. Lea & Febiger. Philadelphia. 1934. (p. 148).

Potts, L.W. : The distribution of nerves to the arteries of the legs. Anat. Anz., 47: 138, 1915.

Laufman, H. , Martin, W.B. AND Tuell, S. : The pattern of vasospasm following acute arterial and venous occlusions. Surg., Gynec. & Obst., 87: 641, 1948.

Bauer, G. : Venographic study of thromboembolic problems. Acta chir. Scandinav. , (Suppl. 61), 84: 1, 1940.

Edwards, E.A. AND Edwards, J.E. : The effect of thrombophlebitis on the venous valve. Surg., Gynec. & Obst., 65: 310, 1937.

Beecher, H.K. : Adjustment of the flow of tissue fluid in the presence of localized sustained high venous pressures as found with varices of the great saphenous system during walking. J. Clin. Investigation, 16: 733, 1937.

Birger, I. : Etiology and therapy of crural ulcers. Nord. Med. (Hygiea). 10: 1249, 1941.

Zilliacus, H. : Correlation between deep thrombosis in lower extremity and ulcer of leg. Nord. med. (Finska läk.-sällsk handl.), 29: 277, 1946.

Bauer, G. : Thrombosis: early diagnosis with aid of phlebography and abortive treatment with heparin. Lancet, 1: 447, 1946.

Jennings, J.E. : Choked leg. Ann. Surg., 98: 928, 1933.

Homans, J. : Thrombophlebitis in the legs. New England J. Med., 218: 594, 1938.

Luke, J.C. : The pathology and treatment of the post-phlebitic leg and its complications . Canad. M.A.J., 61: 270, 1949.

Ochsner, A. AND Debakey, M. : Postphlebitic sequelae. J.A.M.A., 139: 423, 1949 .

Drinker, C.K. , Field, M.E. , Ward, H.K. AND Lyons, C. : Increased susceptibility to local infection following blockage of lymph drainage. Am. J. Physiol., 112: 74, 1935.

De Takats, G. AND Eroy, M.H. : Lymphedema. Angiology, 1: 73, 1950.

Martorell, F. : Chronic edema of lower limbs. Angiology, 2: 434, 1951.

Eger, S.A. AND Casper, S.L. : Etiology of varicose veins from an anatomic aspect. Based on a dissection of 38 adult cadavers. J.A.M.A., 123: 148, 1943 .

Leriche, R. : Sur l'importance de la periphlébite dans la genèse des accidents tardifs consécutifs aux oblitérations veineuses. (Guérison en dix jours d'ulcérations datant de deux ans à la suite d'une liberation arterielle et veineuse.) Bull. et mém. Soc. nat. de chir., 53: 561, 1927.

Homans, J. : Thrombophlebitis of the lower extremities. Ann. Surg., 87: 641, 1928.

Holling, H.E. , Beecher, H.K. AND Linton, R.R. : Study of the tendency to edema formation associated with incompetence of the valves of the communicating veins of the leg. Oxygen tension of the blood contained in varicose veins. J. Clin. Investigation, 17: 555, 1938.

Glasser, S.T. : The postphlebitic leg. Results with femoral vein interruption. Surg., Gynec. & Obst., 89: 541, 1949.

Barrow, D.W. : The Clinical Management of Varicose Veins. Paul B. Hoeber, Inc., New York, Nov., 1948.

Landis, E.M. : The effect of lack of oxygen on the permeability of the capillary wall to fluid and to plasma proteins. Am. J. Phys., 83: 528, 1928.

—, Jonas, L. , Augevine, M. AND Erb, W. : The passage of fluid and protein thru human capillary wall during venous congestion. J. Clin. Investigation, 11: 717, 1932.

Zimmerman, L.M. AND De Takats , G. : The mechanism of thrombophlebitic edema. Arch. Surg., 23: 937, 1931.

De Takats, G. : The management of acute thrombophlebitic edema. J.A.M.A., 100: 34, 1933.

Homans, J. : Deep quiet thrombosis in the lower limb. Surg., Gynec. & Obst., 79: 70, 1944.

—: The late results of femoral thrombophlebitis and their treatment. New England J. Med., 235: 249, 1946 .

Mcmaster, P.D. AND Parsons, R.J. : The effect of pulse on the spread of substances through tissues. J. Exper. Med., 68: 377, 1938.

Naide, M. : Allergic lesions following thrombophlebitis. Ann. Int. Med. , 80: 388, 1947.

Ferreira, J.A. : XX Congr. Arg. de Cir. Cierre de la discusión, 2: 240, 1949.

Bull, D.W. : Phlebography of the lower extremity. S. Clin. N.A., 28: 541, 1948.

Neuhof, H. : Venous Thrombosis and Pulmonary Embolism . Mt. Sinai Hospital Monograph No. 2, Grune and Stratton, N. Y., 1948.

Raymond, G.H. , Adams, G.T. AND Mccorriston , J.R. : Venography in the normal and pathological leg; abstracted, J. Roentgen., 52: 615, 1949.

Welch, C.E. , Faxon, H.H. AND Mcgohey, C.E. : The application of phlebography to the therapy of thrombosis and embolism. Surgery, 12: 163, 1942.

Luke, J.C. : The diagnosis of chronic enlargement of the leg; with the description of a new syndrome. Surg., Gynec. & Obst., 73: 472, 1941.

Mahorner, H. : A method of obtaining venograms of the veins of the extremities. Surg., Gynec. & Obst., 76: 41, 1943.

Mark, J. : Venography. Ann. Surg., 118: 469, 1943.

Felder, D.A. : A method of venography. Radiology, 54: 516, 1950.

Højensgård, I.C. : Phlebography in chronic venous insufficiency of the lower extremity. Acta Rad. Scan., 32: 375, 1949.

Scott, H.W. , JR. AND Roach, J.F. : Phlebography of the leg in the erect position. Ann. Surg., 134: 104, 1951.

Luke, J.C. : Phlebitis of the lower extremity and its sequelae. Canad. M.A.J., 55: 552,1946.

Collins, C.G. AND Ayers, W.B. : Suppurative pelvic thrombophlebitis. III. Surgical technique. Surgery, 30: 319, 1951.

Mclachlin, J. , Paul, R. AND Paterson, J.C. : Antithrombin test for venous thrombosis . Surg., Gynec. & Obst., 94: 297, 1952.

Waller, J.V. : Medical management of the post-phlebitic lower limb. New York Med., 3: 17, 37, 1947.

Snead, C.R. , Lasner, J. , Jenkinson, E.L. AND De Takats , G. : Roentgen therapy of thrombophlebitis. J.A.M.A., 141: 967, 1949 .

Sokolov, R.A. AND Meyers, M.P. : The treatment of deep thrombophlebitis and chronic leg ulcers with acetyl-beta-methylcholine chloride iontophoresis . Am. Heart J., 17: 316, 1939.

Wright, I.S. : Vascular Disease in Clinical Practice. Chicago: Yr. Book Pub. 1948.

Allen, E.V. , Barker, N.W. AND Hines, E.A. : Peripheral Vascular Disease, W. B. Saunders Company, Philadelphia, 1946.

Kessler, R.W. : The surgical management of the post-phlebitic leg. New York Med., 4: 16, 1948.

Cressman, R.D. AND Blalock, A. : The effect of pulse upon the flow of lymph. Proc. Soc. Exper. Biol. & Med., 41: 140, 1939.

Hotz, R. AND Douglass, F.M. , JR.: Sympathectomy and phlebectomy for postphlebitic ulcer. Ohio State M.J., 46: 3, 1950.

Ochsner, A. , Debakey, M. , Decamp, P.T. , RICHMAN, I. M., RAY, C. J., LLEWELLYN, R. C. AND CREECH, O.: Postphlebitic syndrome. Treatment by conservative measures, sympathectomy, and other operative measures. Surgery, 27: 161, 1950.

Shumacker, H.R. , JR.: Surgery in peripheral vascular disease . S. Clin. N.A., pp. 294, April, 1948.

AND Abramson, D.I. : Sympathectomy for stasic ulcer, Surg., Gynec. & Obst., 88: 417, 1949.

Voris, H.C. : Sympathectomy in peripheral vascular disease and hypertension. S. Clin. N.A., Feb., 1947 , p. 139.

Lisker, S. : Chronic leg ulcers. S. Clin. N.A., pp. 1555, Dec., 1947.

Swinton, N.W. AND Graham, F.B. : The treatment of varicose veins of the lower extremities. S. Clin. N.A., 32: 961, 1952.

Lowexberg, E.L. : The treatment of post thrombophlebitic sequelae in the lower extremities. Virginia Med. Monthly, 76: 594, 1949.

Lockhart-Mummery, H.E. AND Smitham, J.H. : Varicose ulcer. A study of the deep veins with special reference to retrograde venography. Brit. J. Surg., 38: 284, 1951.

Linton, R.R. : The communicating veins of the lower leg and the operative technique for their ligation. Ann. Surg., 107: 582, 1938.

— AND Keeley, J.K. : The post-phlebitic ulcer. Am. Heart J., 17: 27, 1939.

Ochsner, A. : Varicosities of the Lower Extremity, Lewis-Walter's Practice of Surgery XII; Chapt. 5-A; pp. 15-26. W. F. Prior Co., Inc., Hagerstown, Md., 1951.

Burrell, R.O. : A consideration of the problem of post-thrombophlebitic eczema, induration and ulceration. The Manitoba Medical Review , 28: 359, 1948.

Homans, J. : The etiology and treatment of varicose ulcers of the leg. Surg., Gynec. & Obst., 24: 300, 1917.

Brown, J.P. , Byars, L.T. AND Blair, V.P. : A study of ulceration of the lower extremity and their repair with thick split skin grafts. Surg., Gynec. & Obst., 63: 331, 1936.

Mahorner, H. : Indurate leg and leg ulcers. A clinical study of their etiology and treatment . Surg., Gynec. & Obst., 88: 115, 1949.

Macey, H. : A new surgical procedure for lymphedema of the extremities: report of a case. Proc. Staff. Meet., Mayo Clin., 15: 49, 1940.

Poth, E.J. , Barnes, S.R. AND Ross, G.T. : A new operative treatmenl for elephantiasis. Surg., Gynec. & Obst., 84: 642, 1947.

Campbell, D.A. , Glas, W.W. AND Musselman , M.M. : The surgical treatment of massive lymphedema of the lower extremities. Surgery, 30: 763, 1951.

Pratt, G.H. : Surgical Management of Vascular Diseases. Lea & Febiger , Philadelphia, 1949 (p. 398).

Rees, H.C. AND Slevin, J.G. : Surgical management of vascular leg ulcers . Surgery, 21: 575, 1947.

Seligman, B. : The post-phlebitic syndrome. A method of treatment. Angiology, 2: 350, 1951.

Grant, J.C.B. : A Method of Anatomy. 4th Ed. The Williams & Wilkins Co., Baltimore. 1948.

Mcpheeters, H.O. AND Alexander , H.A. : Lumbar sympathetic block and that postphlebitic leg. Minn. Med., 29: 43, 1946.

Luke, J.C. : The deep vein valves. Surgery , 29: 381, 1951.

Partridge, A.J. : Letters to the editor. Varicose ulcers . Lancet, 1: 818, 1952.

Veal, J.R. AND Hussey, H.H. : Methods for measurement of pressures in anticubital and popliteal veins during exercise. M. Ann. District of Columbia, 9: 71, 1940.

Ross, C.F. AND Keele, K.D. : Post mortem arteriography in "normal" lower limbs. Angiology, 2: 374, 1951.

Migliaccio, A.V. AND Ricci, E.A. : Surgical treatment of varicose veins associated with subcutaneous fibrosis. Surgery, 29: 811, 1951.