PiedrahitaJAZhangSHHagamanJROliverPMMaedaN. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc Natl Acad Sci U S A. 1992;89(10):4471–4475.
2.
KolovouGAnagnostopoulouKMikhailidisDPCokkinosDV. Apolipoprotein E knockout models. Curr Pharm Des. 2008;14(4):338–351.
3.
ArdansJABlumAManganPRWientroubSCannonRO3rd, WahlLM. Raloxifene-mediated increase in matrix metalloproteinase-1 production by activated monocytes. Arterioscler Thromb Vasc Biol. 2001;21(8):1265–1268.
4.
RosenfeldMEKauserKMartin-McNultyBPolinskyPSchwartzSMRubanyiGM. Estrogen inhibits the initiation of fatty streaks throughout the vasculature but does not inhibit intra-plaque hemorrhage and the progression of established lesions in apolipoprotein E deficient mice. Atherosclerosis. 2002;164(2):251–259.
5.
ArteroATarínJJCanoA. The adverse effects of estrogen and selective estrogen receptor modulators on hemostasis and thrombosis. Semin Thromb Hemost. 2012;38(8):797–807.
6.
SimonciniTMannellaPFornariLCarusoAVaroneGGenazzaniAR. Genomic and non-genomic effects of estrogens on endothelial cells. Steroids. 2004;69(8-9):537–542.
7.
JeanesHLTaborCBlackDEderveenAGrayGA. Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)alpha agonist and unaffected by an ER beta antagonist. J Endocrinol. 2008;197(3):493–501.
8.
JensenEV. On the mechanism of estrogen action. Perspect Biol Med. 1962;6:47–59.
9.
GreenSWalterPKumarV. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature. 1986;320(6058):134–139.
10.
ThomasPPangYFilardoEJDongJ. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology. 2005;146(2):624–632.
11.
HaasEMeyerMRSchurrU. Differential effects of 17beta-estradiol on function and expression of estrogen receptor alpha, estrogen receptor beta, and GPR30 in arteries and veins of patients with atherosclerosis. Hypertension. 2007;49(6):1358–1363.
AokiN.SiegfriedM.LeferAM. Anti-EDRF effect of tumor necrosis factor in isolated, perfused cat carotid arteries. Am J Physiol. 1989;256(5 Pt 2):H1509–H1512.
14.
AhmadMZhangYPapharalambusCAlexanderRW. Role of isoprenylcysteine carboxyl methyltransferase in tumor necrosis factor-α stimulation of expression of vascular cell adhesion molecule-1 in endothelial cells. Arterioscler Thromb Vasc Biol. 2002;22(5):759–764.
15.
PaikJKChaeJSKangRKwonNLeeSH, Lee JH. Effect of age on atherogenicity of LDL and inflammatory markers in healthy women [published online September 25, 2012]. Nutr Metab Cardiovasc Dis. 2012. pii: S0939-4753(12)00191–3. doi: 10.1016/j.numecd.2012.08.002.
16.
PalmieriDPeregoPPalomboD.Estrogen receptor activation protects against TNFα-induced endothelial dysfunction. Angiology. 2014;65(1):17–21.
17.
NeumannPGertzbergNJohnsonA. TNF-alpha induces a decrease in eNOS promoter activity. Am J Physiol Lung Cell Mol Physiol. 2004;286(2):L452–L459.
18.
FukudaDShimadaKTanakaA. Comparison of levels of serum matrix metalloproteinase-9 in patients with acute MI versus unstable angina pectoris versus stable angina pectoris. Am J Cardiol. 2006;97(2):175–180.
19.
HenrikssonPSamnegardAWallenNH. Sex hormone sensitivity of matrix metalloproteinases 6 and 9. Eur J Clin Invest. 2008;38(5):336–337.
20.
LaviSYangEHPrasadA. The interaction between coronary endothelial dysfunction, local oxidative stress, and endogenous nitric oxide in humans. Hypertension. 2008;51(1):127–133.
21.
RauchBHMuschenbornBBraunMWeberAASchrorK. ICAM-1 and p38 MAPK mediate fibrinogen-induced migration of human vascular smooth muscle cells. Eur J Pharmacol. 2007;577(1-3):54–57.
22.
TitoloDMayerCMDhillonSSCaiFBelshamDD. Estrogen facilitates both phosphatidylinositol 3-kinase/Akt and ERK1/2 mitogen-activated protein kinase membrane signaling required for long-term neuropeptide Y transcriptional regulation in clonal, immortalized neurons. J Neurosci. 2008;28(25):6473–6482.
23.
RossR. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999;340(2):115–126.
24.
MendelsohnME. Protective effects of estrogen on the cardiovascular system. Am J Cardiol. 2002;89(12A):12E–18E.
25.
SitesCKTothMJCushmanM. Menopause-related differences in inflammation markers and their relationship to body fat distribution and insulin-stimulated glucose disposal. Fertil Steril. 2002;77(1):128–135.
26.
ZhangHParkYWuJ. Role of TNF-alpha in vascular dysfunction. Clin Sci (Lond). 2009;116(3):219–230.
27.
SrivastavaSWeitzmannMNCenciSRossFPAdlerSPacificiR. Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD. J Clin Invest. 1999;104(4):503–513.
28.
XingDFengWMillerAP. Estrogen modulates TNF-α-induced inflammatory responses in rat aortic smooth muscle cells through estrogen receptor-β activation. Am J Physiol Heart Circ Physiol. 2007;292(6):H2607–H2612.
29.
Caulin-GlaserTWatsonCAPardiRBenderJR. Effects of 17beta-estradiol on cytokine-induced endothelial cell adhesion molecule expression. J Clin Invest. 1996;98(1):36–42.
30.
ChoiEM. Apigenin increases osteoblastic differentiation and inhibits tumor necrosis factor-alpha-induced production of interleukin-6 and nitric oxide in osteoblastic MC3T3-E1 cells. Pharmazie. 2007;62(3):216–220.
31.
PaolettiTFallariniSGugliesiFMinassiAAppendinoGLombardiG. Anti-inflammatory and vascular protective properties of 8-prenylapigenin. Eur J Pharmacol. 2009;620(1-3):120–130.
32.
Collins-BurowBMBurowMEDuongBNMcLachlanJA. Estrogenic and antiestrogenic activities of flavonoid phytochemicals through estrogen receptor binding-dependent and -independent mechanisms. Nutr Cancer. 2000;38(2):229–244.
33.
PrelevicGMKwongPByrneDJJagroopIAGinsburgJMikhailidisDP. A cross-sectional study of the effects of hormon replacement therapy on the cardiovascular disease risk profile in healthy postmenopausal women. Fertil Steril. 2002;77(5):945–951.
34.
MoscaLBenjaminEJBerraK. Effectiveness-based guidelines for the prevention of cardiovascular disease in women—2011 update: a guideline from the American Heart Association. Circulation. 2011;123(11):1243–1262.
