Why the US Center for Medicare and Medicaid Services Should Not Extend Reimbursement Indications for Carotid Artery Angioplasty/Stenting

Mayberg MR Wilson SE Yarsu F . Carotid endarterectomy and prevention of cerebral ischemia in symptomatic carotid stenosis. Veterans Affairs Cooperative Studies Program 309 Trialist Group. JAMA. 1991;266(23):3289–3294.

The European Carotid Surgery Trialists' Collaborative Group. Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST). Lancet. 1998;351(9113):1379–1387.

North American Symptomatic Carotid Endarterectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med. 1991;325(7):445–453.

Hobson RW 2nd Weiss DG Fields WS . Efficacy of carotid endarterectomy for asymptomatic carotid stenosis. The Veterans Affairs Cooperative Study Group. N Engl J Med. 1993;328(4):221–227.

Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. Endarterectomy for asymptomatic carotid artery stenosis. JAMA. 1995;273(118):1421–1428.

Halliday A Mansfield A Marro J . Prevention of disabling and fatal strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled trial. Lancet. 2004;363(9420):1491–1502.

Halliday A Harrison M , Hayter E, et al. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): A multicentre randomised trial. Lancet. 2010;376(9746):1074–1084.

Rerkasem K Rothwell PM . Carotid endarterectomy for symptomatic carotid stenosis. Cochrane Database Syst Rev. 2011;(4): CD001081.

Chambers BR Donnan GA . Carotid endarterectomy for asymptomatic carotid stenosis. Cochrane Database Syst Rev. 2005;(4): CD001923.

Abbott AL . Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: Results of a systematic review and analysis. Stroke. 2009;40(10): e573–e583.

Abbott AL . Why all the landmark trials supporting surgery to prevent strokes from carotid stenosis are now obsolete: when is carotid intervention now indicated? Presented at the 37th Annual Vascular and Endovascular Issues, Techniques and Horizons (VEITHsymposium)2010: New York Hilton, New York City. http://www.veithsymposium.org/pdf/vei/3766.pdf. Accessed January 18, 2012.

Naylor AR Gaines P Rothwell P . Who benefits most from interventions for asymptomatic carotid stenosis: Patients or professionals? Eur J Vasc Endovasc Surg. 2009;37(3):625–632.

Naylor AR . What is the current status of invasive treatment of extracranial carotid artery disease? Stroke. 2011;42(7):2080–2085.

Spence JD Coates V Li H . Effects of intensive medical therapy on microemboli and cardiovascular risk in asymptomatic carotid stenosis. Arch Neurol. 2010;67(2):180–186.

Rothwell PM Coull AJ Giles MF . Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet. 2004;363(9425):1925–1933.

Broderick JP . The challenges of intracranial revascularization for stroke prevention. N Engl J Med. 2011;365(11):1054–1055.

Chimowitz MI Lynn MJ Derdeyn CP . Stenting versus aggressive medical therapy for intracranial arterial stenosis. N Engl J Med. 2011;365(11):993–1003.

Unal B Critchley JA Fidan D Capewell S . Life-years gained from modern cardiological treatments and population risk factor changes in England and Wales, 1981-2000. Am J Public Health. 2005;95(1):103–108.

Goldstein LB Bushnell CD Adams RJ . Guidelines for the primary prevention of stroke. A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2 011;42(2):517–584.

Furie KL Kasner SE Admas RJ . Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: A guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42(1):227–276.

Goessens BM Visseren FL Kapelle LJ Algra A van der Graaf Y . Asymptomatic carotid artery stenosis and the risk of new vascular events in patients with manifest arterial disease: The SMART study. Stroke. 2007;38(5):1470–1475.

Markus HS King A Shipley M . Asymptomatic embolisation for prediction of stroke in the Asymptomatic Carotid Emboli Study (ACES): a prospective observational study. Lancet Neurol. 2010;9(7):663–671.

Marquardt L Geraghty OC Mehta Z Rothwell PM . Low risk of ipsilateral stroke in patients with asymptomatic carotid stenosis on best medical treatment: a prospective, population-based study. Stroke. 2010;41(1): e11–e17.

Brott TG Hobson RW 2nd Howard G . Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med. 2010;363(1):11–23.

Brooks WH McClure RR Jones MR Coleman TL Breathitt L . Carotid angioplasty and stenting versus carotid endarterectomy for treatment of asymptomatic carotid stenosis: a randomized trial in a community hospital. Neurosurgery. 2004;54(2):318–324; discussion 324-325.

Yadav JS Wholey MH Kuntz RE . Protected carotid-artery stenting versus endarterectomy in high-risk patients. N Engl J Med. 2004;351(15):1493–1501.

Brott TG Halperin JL Abbara S . 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery. Stroke. 2011;42(8): e420–63.

Sidawy AN Zwolak RM White RA Siami FS Schermerhorn ML Sicard GA ; Outcomes Committee for the Society for Vascular Surgery. Risk-adjusted 30-day outcomes of carotid stenting and endarterectomy: results from the SVS vascular registry. J Vasc Surg. 2009;49(1):71–79.

Rockman CB Garg K Jacobowitz GR . Outcome of carotid artery interventions among female patients, 2004 to 2005. J Vasc Surg. 2011;53(6):1457–1464.

Giles KA Hamdan AD Pomposelli FB Wyers MC Schermerhorn ML . Stroke and death after carotid endarterectomy and carotid artery stenting with and without high risk criteria. J Vasc Surg. 2010;52(6):1497–1504.

Blackshear JL Roubin GS Hill MD Leimgruber PP . Myocardial infarction after carotid stenting and endarterectomy: results from the carotid revascularization endarterectomy versus stenting trial. Circulation. 2011;123(22):2571–2578.

Naylor AR . Hearts and Minds. Eur J Vasc Endovasc Surg. 2012; 43:1–3.

Paraskevas KI Moore WS Veith FJ . Cost implications of more widespread carotid artery stenting consistent witht the American College of Cardiology/American Heart Association Guideline. J Vasc Surg. 2012;55:585–587.

Hertzer NR . The nationwide inpatient sample may contain inaccurate data for carotid endarterectomy and carotid stenting. J Vasc Surg. 2012;55:263–266.

Hankey GJ . Ischaemic stroke–prevention is better than cure. J R Coll Physicians Edinb. 2010;40(1):56–63.

Spence JD Pelz D Veith FJ . Asymptomatic Carotid Stenosis: identifying patients at high enough risk to warrant endarterectomy or stenting. Stroke. 2011;42. Published online July 28, 2011.

Naylor AR . Time to rethink management strategies in asymptomatic carotid artery disease. Nat Rev Cardiol. 2012;9:116–24.

Bell P . Best medical treatment is best for most asymptomatic cases. Presented at the 38th Annual Vascular and Endovascular Issues, Techniques and Horizons (VEITHsymposium) 2011: New York Hilton, New York City. http://www.veithsymposium.org/pdf/vei/4583.pdf. Accessed January 18, 2012.

Redberg RF . Squandering Medicare's money. New York Times, 25th May 2011. New York Times. 26th May 2011 PA35. http://www.nytimes.com/2011/05/26/opinion/26redberg.html. Accessed January 18, 2012.

Nallamothu BK Lu M Rogers MA Gurm HS Birkmeyer JD . Physician specialty and carotid stenting among elderly medicare beneficiaries in the United States. Arch Intern Med. 2011;171(20):1804–1810.

Berkowitz SA Redberg RF . Dramatic increases in carotid stenting despite nonconclusive data. Arch Intern Med. 2011;171(20):1794–1795.

Paraskevas KI Veith FJ Riles TS Moore WS . Is carotid artery stenting a fair alternative to carotid endarterectomy for symptomatic carotid artery stenosis? Eur J Vasc Endovasc Surg. 2011;41(6):717–719.

Paraskevas KI Veith FJ Riles TS Moore WS . Is carotid artery stenting a fair alternative to carotid endarterectomy for symptomatic carotid artery stenosis? A commentary on the AHA/ASA guidelines. J Vasc Surg. 2011;54(2):541–543; discussion 543.

Silver FL Mackey A Clark WM . Safety of Stenting and Endarterectomy by Symptomatic Status in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST). Stroke. 2011;42(3):675–680.

Mas JL Chatellier G Beyssen B . Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis. N Engl J Med. 2006;355(16):1660–1671.

Ederle J Dobson J Featherstone RL . Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial. Lancet. 2010;375(9719):985–997.

Mas JL Trinquart L Leys D . Endarterectomy versus angioplasty in patients with symptomatic severe carotid stenosis (EVA-3S) trial: results up to 4 years from a randomised, multicentre trial. Lancet Neurol. 2008;7(10):885–892.

Bonati LH Dobson J Algra A . Short-term outcome after stenting versus endarterectomy for symptomatic carotid stenosis: a preplanned meta-analysis of individual patient data. Lancet. 2010;376(9746):1062–1073.

Economopoulos KP Sergentanis TN Tsivgoulis G Mariolis AD Stefanadis C . Carotid artery stenting versus carotid endarterectomy: A comprehensive meta-analysis of short-term and long-term outcomes. Stroke. 2011;42(3):687–692.

Paraskevas KI Mikhailidis DP Moore WS Veith FJ . Optimal contemporary management of symptomatic and asymptomatic carotid artery stenosis. Vascular. 2011;19(3):117–120.

Carotid Stenting Guidelines Committee: an Inter-collegiate Committee of the RACP (ANZAN, CSANZ), RACS (ANZSVS) and RANZCR. Guidelines for patient selection and performance of CAS. Intern Med J. 2011;41(4):344–347.

Bonati LH Fraedrich G. Age modifies the relative risk of stenting versus endarterectomy for symptomatic carotid stenosis—a pooled analysis of EVA-3 S, SPACE and ICSS. Eur J Vasc Endovasc Surg. 2011;41(2):153–158.

Bonati LH Jongen LM Haller S . New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS). Lancet Neurol. 2010;9(4):353–362.

Eckstein HH Ringleb P Allenberg JR . Results of the Stent-Protected Angioplasty versus Carotid Endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective, randomised trial. Lancet Neurol. 2008;7(10):893–902.

Bonati LH Ederle J McCabe DJ . Long-term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial. Lancet Neurol. 2009;8(10):908–917.

Arquizan C Trinquart L Touboul PJ . Restenosis is more frequent after carotid stenting than after endarterectomy: The EVA-3S study. Stroke. 2011;42(4):1015–1020.