Dolichoarteriopathies consist of tortuosity, kinking, or coiling of the extracranial carotid arteries. Some authors consider these alterations a consequence of atherosclerotic vessel remodeling, while others ascribe them to anatomical variations of embryological origin. The objective was to establish whether carotid dolichoarteriopathies belonged to a congenital origin or to acquired conditions. Color Doppler ultrasonography of neck vessels was performed in 885 participants, whose age ranged from 1-day-old infants to 90-year-old adults. Prevalence of kinking and coiling was evaluated, and it was related to the presence of cardiovascular risk factors. Prevalence of either kinking or coil of carotid arteries showed no increase with age, as it was comparable across all ages; furthermore, frequency of these alterations showed no relationship to cardiovascular risk factors nor to the presence of atheromatous plaques. These findings suggest that carotid dolichoarteriopathies are a result of alterations in embryological development rather than vascular remodeling secondary to aging and/or atherosclerosis.
Endarterectomy for asymptomatic carotid artery stenosis.Executive Committe for the Asymptomatic Carotid Atherosclerosis Study. JAMA. 1995;273(18):1421-1428.
Schechter DCDolichocarotid syndrome. Cerebral ischemia related to cervical carotid artery redundancy with kinking: PartI. NY State. J Med. 1979;79(9):1391-1397.
6.
Macchi C., Gulisano M., Giannelli F., Catini C., Pratesi C., Pacini P.Kinking of the human internal carotid artery: A statistical study in 100 healthy subjects by echocolor Doppler. J Cardiovasc Surg. 1997;38(6):629-637.
7.
Pellegrino L. , Prencipe G., Vairo F.Dolicho-arteriopathies (kinking, coiling, tortuosity) of the carotid arteries: study by color Doppler ultrasonography . Minerva Cardioangiol. 1998 ;46(3):69-76.
8.
Pancera P., Ribul M., De Marchi S., Arosío E., Lechi A.Prevalence of morphological alterations in cervical vessels: A colour duplex ultrasonography study in a series of 3300 subjects. Int Angiol . 1998;17(1):22-27.
9.
Mukherjee D. , Inahara T.Management of the tortuous intemal carotid artery. Am J Surg. 1985;149(5):651-655.
10.
Koskas F., Bahnini A., Waldern N., Kieffer E.Stenotic coiling and kinking of the internal carotid artery. Ann Vasc Surg. 1993;7(6):530-540.
11.
Aleksic M., Schutz G., Gerth S., Mulch J.Surgical approach to kinking and coiling of the internal carotid artery . J Cardiovasc Surg (Torino). 2004;45(1):43-48.
12.
Ballotta E. , Thiene G., Baracchini C., et al. Surgical vs. medical treatment for isolated internal carotid artery elongation with coiling or kinking in symptomatic patients: a prospective randomized clinical study . J Vasc Surg. 2005;42(5):838-846.
13.
Togay-Isikay C., Kim J., Betterman K., et al. Carotid artery tortuosity, kinking, coiling: stroke risk factor, marker, or curiosity?Acta Neurol Belg. 2005;105(2):68-72.
14.
Price RA, Vawter GFArterial fibromuscular dysplasia in infancy and childhood. Arch Pathol. 1972;93(5): 419-423.
15.
Ghilardi G. , De Monti M., Trimarchi S., Bortolani E.Prevalenza del kinking carotideo in una popolazione residente. Minerva Cardioangiol. 1993;41(4):129-132.
16.
Ghilardi G. , Longhi F., De Monti M., Bortolani E.Kinking Carotideo ed ipertensione arteriosa . Minerva Cardioangiol. 1993;41(7-8):287-292.
17.
Quattlebaum J. Jr, Upson E., Neville RLStroke associated with elongation and kinking of the internal carotid artery. Ann Surg. 1959;150:824-832.
18.
Pancera P., Ribul M., Presciuttini B., Lechi A.Prevalence of carotid artery kinking in 590 consecutive subjects evaluated by Echodoppler Is there a correlation with arterial hypertension? . J Intern Med. 2000;248(1):7-12.
19.
Oliviero U. , Scherillo G., Casaburi C., et al. Prospective evaluation of hypertensive patients with carotid kinking and coiling: an ultrasonographic 7-year study . Angiology. 2003;54(2):169-175.
20.
Kelly ABTortuosity of the internal carotid in relation to the pharynx. J Laring. 1925;40:15-20.
21.
Harrison J. , Davalos P. Cerebral ischemia. Arch Surg. 1962;84:109-112.
22.
Etheredge SN , Effeney DJ, Ehrenfeld WKSymptomatic extrinsic compression of the cervical carotid artery. Arch Neurol. 1984;41(6):672-673.
23.
Del Corso L. , Moruzzo D., Conte B., et al. Tortuosity, kinking and coiling of the carotid artery: Expression of atherosclerosis or aging? Angiology. 1998;49(5): 361-371.
24.
Sarkari NBS , Macdonald H., Bickerstaff E.Neurological manifestations associated with internal carotid loops and kinks in children. J Neurol Neurosurg Psychiatr. 1970; 33(2):194-200.
25.
Perdue GD, Barreca JP, Smith RB, King OWThe significance of elongation and angulation of the carotid artery: A negative view. Surgery. 1975;77(1):45-52.
26.
Cairney J.Tortuosity of the cervical segment of the internal carotid artery . J Anat (Lond). 1924;59(pt 1):87-96.
27.
Ochsner JL, Hughes P., Leonard GL, Milis N.Elastic tissue dysplasia of the internal carotid artery. Ann Surg. 1997;185(6):684-691.
28.
Starr DS, Lawrie GM, Morris GCFibromuscular disease of carotid arteries: long results of graduated internal dilatation. Stroke. 1981;12(2):196-199.
29.
Mettinger KL , Ericson K.Fibromuscular dysplasia and the brain. Stroke. 1982;13(1):46-52.
30.
Danza R., Baldizan J, Navarro T.Surgery of carotid kinking and fibromuscular dysplasia. J Cardiovasc Surg. 1983;24(6):628-633.
