Essential thrombocythemia (ET) can cause systemic vascular thrombosis, but involvement of coronary arteries in the setting of ET is rare. This report describes a case of acute myocardial infarction (MI) in a patient with ET. A 67-year-old man with ET complained of severe acute chest pain. Emergent coronary angiography revealed subtotal thrombotic occlusion of the left main trunk (LMT) coronary artery. Coronary angioplasty and stenting were performed successfully. Coronary angiography 4 weeks later revealed no significant restenosis. The patient has done well after primary coronary stenting with the use of only an antiplatelet agent to treat the thrombocythemia.
Get full access to this article
View all access options for this article.
References
1.
Hattori A, Nagayama R, Kishi K, et al: Primary thrombocythemia in Japan: A survey of 225 patients. Leuk Lymph4:177-186, 1991.
2.
Okayasu N, Murata M, Ueda A, et al: Primary thrombocythemia and myocardial infarction in a 26-year-old woman with normal coronary arteriogram. Jpn Heart J22:439-445, 1981.
3.
Takahashi H, Koeda T, Usui Y, et al: A case of essential hemorrhagic thrombocythemia associated with subendocardial infarction and acute renal failure (in Japanese). Jpn Intern Med72:569-575, 1983.
4.
Douste-Blazy JW, Taudou MJ, Delay M, et al: Essential thrombocythemia and recurrent myocardial infarction. Lancet27:992, 1984.
5.
Kaya H, Gundogdu M, Tekin SB, et al: Essential thrombocythemia and recurrent myocardial infarction. Clin Lab Haem22:161-162, 2000.
6.
Yano K, Takeyama H, Watanabe E, et al: A case of essential thrombocythemia associated with myocardial and cerebral infarction (in Japanese). Naika57:177-179, 1986.
7.
Ushiyama K, Aoki Y, Ninomiya H, et al: A case of essential thrombocythemia with myocardial infarction (in Japanese). Naika60:1399-1402, 1987.
8.
Louwerenburg JW, Suttorp MJ, Herre Kingma J: Aspirin withdrawal in a patient with essential thrombocythemia: Possible cause of myocardial infarction. Am J Med83:1175, 1987.
9.
Suzuki A, Suzuki F, Takahata H, et al: Essential thrombocythemia associated with myocardial infarction—a case report (in Japanese). Shinzo20:444-450, 1988.
10.
Hamada Y, Matsuda Y, Fujii B, et al: Multiple coronary thrombosis in a patient with thrombocytosis. Clin Cardiol12:723-724, 1989.
11.
Furui H, Yamada Y, Tsuzuki M, et al: A case of essential thrombocythemia associated with acute myocardial infarction (in Japanese). Shinzo22:180-184, 1990.
12.
Esteves Filho A, Costa Fde A, Lima AA, et al: Essential thrombocythemia and acute myocardial infarction treated with rescue coronary angioplasty. Arq Bras Cardiol73:97-102, 1999.
13.
Michaels AD, Whisenant B, MacGregor JS: Multivessel coronary thrombosis treated with abciximab (ReoPro®) in a patient with essential thrombocythemia. Clin Cardiol21:134-138, 1998.
14.
Turgut T, Harjai KJ, Edupuganti R, et al: Acute coronary occlusion and in-stent thrombosis in a patient with essential thrombocythemia. Cathet Cardiovasc Diagn45:428-433, 1998.
15.
Cortelazzo S, Finazzi G, Ruggeri M, et al: Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis. N Engl J Med332:1132, 1995.
