A case of sinus node dysfunction is reported secondary to severe sinus node artery obstruc tion 3 years after orthotopic heart transplantation. The patient first presented with frequent dizzy spells and presyncopal episodes for 3 months and then recurrent syncope in the presence of an acute myocardial infarction. Coronary angiography showed a diffusely narrowed sinus node artery without any apparent collateral vessels. The sinus node artery had had only minimal distal disease 3 months previously. A dual chamber permanent pacemaker was implanted with significant improvement in clinical symptoms.
Get full access to this article
View all access options for this article.
References
1.
Scott CD, Dark JH, McComb JM: Sinus node function after cardiac transplantation. J Am Coll Cardiol24:1334-1341, 1994 .
2.
DiBiase A., Tse TM, Schnittger I., et al: Frequency and mechanism of bradycardia in cardiac transplant recipients and need for pacemakers. Am J Cardiol67:1385-1389, 1991.
3.
Weinfeld MS, Kartashov A., Piana R., et al: Bradycardia : A late complication following cardiac transplantation . Am J Cardiol78:969-971, 1996.
4.
Jing HL, Hu BJ: Sudden death caused by stricture of the sinus node artery. Am J Forensic Med Pathol18:360-362, 1997.
5.
Osborn LA, Icenogle M.: Resolution of exercise intolerance secondary to ischemic sinus node dysfunction following percutaneous transluminal angioplasty. Cathet Cardiovasc Diagn42:44-47, 1997.
6.
Kyriakidis M. , Trikas A., Triposkiadis F., et al: Sinus node dysfunction in acute inferior myocardial infarction. Role of sinus node artery and clinical course in patients with one-vessel coronary artery disease. Cardiology88:166-169, 1997.
7.
Kyriakidis M. , Barbetseas J., Antonopoulos A., et al: Early atrial arrhythmias in acute myocardial infarction. Role of the sinus node artery. Chest101:944-947, 1992.
8.
Wong AK, Marais HJ, Jutzy K., et al: Isolated atrial infarction in a patient with single vessel disease of the sinus node artery. Chest100:255-256, 1991.
9.
Mehta PM, Reddy R., Lesser J., et al: Severe bradycardia following electrical cardioversion for atrial tachyarrhythmias in patients with acute myocardial infarction. Chest97:241-242, 1990.
10.
Melton IC, Gilligan DM, Wood MA, et al: Optimal cardiac pacing after heart transplantation. PACE22:1510-1527, 1999.
11.
Kennel AJ, Titus JL: The vasculature of the human sinus node. Mayo Clin Proc47:556-561, 1972.
12.
Nerantzis CE , Toutouzas P., Avgoustakis D.: The importance of the sinus node artery in the blood supply of the atrial myocardium. Acta Cardiol38:35-47, 1983.
13.
Taylor JR, Taylor AJ: The relationship between the sinus node and the right atrial appendage . Can J Cardiol13:85-92, 1997.
14.
Kyriakidis M., Vyssoulis G., Barbetseas J., et al: A clinical angiographic study of the arterial blood supply to the sinus node. Chest94:1054-1057, 1988.
15.
Nerantzis C. , Avgoustakis D.: An S-shaped atrial artery supplying the sinus node area. An anatomical study. Chest78:274-278, 1980.
16.
Rothman SA, Jeevanandam V., Combs WG, et al: Eliminating bradyarrhythmias after orthotopic heart transplantation . Circulation94(suppl II):278-282, 1996.
17.
Gao SZ, Alderman EL, Schroeder JS, et al: Accelerated coronary vascular disease in the heart transplant patient: Coronary arteriographic findings. J Am Coll Cardiol12:334-340, 1988.