A 25-year-old man with low cardiac risks underwent coronary arteriography because of chest pain at rest. His only risk factors for coronary artery disease was smoking. Both right and left coronary arteries were ectatic and the left anterior descending artery was obstructed. In the acetylcholine provocation test, the left circumflex coronary artery showed severe constriction. Thus, this patient was diagnosed as having a combination of variant angina and occlusive coronary artery disease.
Get full access to this article
View all access options for this article.
References
1.
Hatch FT, Reissell PK, Poon-King Tmw, et al: A study of coronary heart disease in young men. Characteristics and metabolic studies of the patients and comparison with age-matched healthy men. Circulation33:679-703, 1966.
2.
Walker WJ, Gregoratos MG: Myocardial infarction in young men. Am J Cardiol19:339-343, 1967.
3.
Glover MU, Kuber MT, Warren SE, et al: Myocardial infarction before age 36: Risk factor and arteriographic analysis. Am J Cardiol49:1600-1603, 1982 .
4.
Enos WF JrBeyer, JC, Holmes RH: Pathogenesis of coronary disease in American soldiers killed in Korea . JAMA158:912-914, 1955.
5.
McNamara JJ, Molot MA, Stremple JF, et al: Coronary artery disease in combat casualties in Vietnam. JAMA216:1185-1187, 1971.
6.
Welch CC, Proudfit WL, Sones FM Jr, et al: Cinecoronary arteriography in young men. Circulation42:647-652, 1970.
7.
Davia JE, Hallal FJ, Cheitlin MD, et al: Coronary artery disease in young patients: Arteriographic and clinical review of 40 cases aged 35 and under. Am Heart J87:689-696, 1974.
8.
Virmani R., McAllister HA Jr: Coronary heart disease at young age: A report of 187 autopsy patients who died of severe coronary atherosclerosis. Cardiovasc Rev Rep5:799-810, 1984.
9.
Genda A., Nakayama A., Shimizu M., et al: Coronary angiographic characteristics in Japanese patients with heterozygous familial hypercholesterolemia. Atherosclerosis66:29-36, 1987.
Rose V., Wilson G., Steiner G.: Familial hypercholesterolemia : Report of coronary death at age 3 in a homozygous child and prenatal diagnosis in a heterozygous sibling. J Pediatr100:757-759, 1982.
12.
Mehan VK, Salzmann C., Pfammatter J.- P, et al: Left main coronary angioplasty in a 10-year-old boy with homozygous familial hypercholesterolemia. Cathet Cardiovasc Diagn29:24-27, 1993.
13.
Roman C., Gooch AS, Maranhao V.: Far-advanced coronary artery atherosclerosis in a 25-year-old man . J Am Osteopath Assoc86:496-498, 1986.