Recent reports have documented the potentially catastrophic consequences of dehydration induced by vigorous exercise in otherwise healthy individuals. A case of acute pancreatitis secondary to exercise-induced dehydration is presented, and the literature of dehydration-induced syndromes, both research and clinical, is reviewed. The goal of this case report is to heighten awareness of dehydration as a potential cause of acute pancreatitis.
Get full access to this article
View all access options for this article.
References
1.
JaakkolaM, NordbackI.Pancreatitis in Finland between 1970 and 1989.Gut1993;34:1255–60.
2.
MannDV, HershamMJ, HittingerR, GlazerG.Multicentre audit of death from acute pancreatitis.Br J Surg1994;81:890–3.
3.
WarshawAL.Ischemia- and reperfusion-related injury in pancreatitis.Dig Dis Sci41(5):821–2, 1996.
4.
Fernandez-delCastillo C, HarringerW, WarshawAL, . Risk factors for pancreatic cellular injury after cardiopulmonary bypass.N Engl J Med1991;325:832–7.
5.
NakanoS, MugikuraM, EndohM, . Acute pancreatitis with diabetic ketoacidosis associated with hypermyoglobinemia, acute renal failure, and DIC.J Gastroenterol1996;31:623–6.
6.
BelmanAB.Renal vein thrombosis in infancy and childhood: A contemporary survey.Clin Pediatr1976;15:1033–44.
7.
ReimoldEW, WittelRA.Renal venous thrombosis in children: Changes in management.South Med J1983;76(10):1277–84.
8.
AmitaiI, GoderK, HusseiniN, RoussoM.Hypernatremic dehydration complicated by peripheral gangrene in infancy.Isr J Med Sci1983;19:538–40.
9.
MouzardD, Le Tan VinhA, PloussardJP.Dehydration with thrombosis of the abdominal aorta in a neonate.Ann Pediatr1982;29:132–4.
10.
LineD, WhitakerN.Dehydration and thromboembolism.Br Med J1979;1(6179):1708.
11.
CroylePH, PlaceRA, HilgenbergAD.Massive pulmonary embolism in a high school wrestler.JAMA1979;241:827–8.
12.
Hyperthermia and dehydration-related deaths associated with intentional rapid weight loss in three collegiate wrestlers— North Carolina, Wisconsin, and Michigan, November-December 1997. MMWR Morbid Mortal Wk Rep 1998;47:105–8.
13.
GartyBZ.Furosemide-associated fever: Drug fever or dehydration fever?J Pediatr1997;130:499–500.
14.
ReubiFC.Hemodynamic changes in isotonic dehydration.Contributions Nephrol1980;21:55–61.
HotterG, ClosaD, GelpiE, PratsN, Rosello-CatafauJ.Role of xanthine oxidase and eicosanoids in development of pancreatic ischemia-reperfusion injury.Inflammation1995;19:469–78.
17.
HoffmannTF, WaldnerH, MessmerK.The bradykinin antagonist CP-0597 can limit the progression of postischemic pancreatitis.Immunopharmacology1996;33:243–6.
18.
SiechM, WeberH, LetkoG, . Similar morphological and intracellular biochemical changes in alcoholic acute pancreatitis and ischemic acute pancreatitis in rats.Pancreas1997;14:32–8.
19.
KlarE, SchrattW, FoitzikT, . Impact of microcirculatory flow pattern changes on the development of acute edematous and necrotizing pancreatitis in rabbit pancreas.Dig Dis Sci1994;39:2639–44.
BroePJ, ZuidemaGD, CameronJL.The role of ischemia in acute pancreatitis: Studies with an isolated perfused canine pancreas.Surgery1982;91:377–82.
22.
SanfeyH, BroePJ, CameronJL.Experimental ischemic pancreatitis: Treatment with albumin.Am J Surg1985;150:297–300.
23.
BroePJ, CameronJL.Experimental oedematous pancreatitis: The effects of ischaemia.Ir J Med Sci1986;155:83–8.
24.
SanfeyH, BulkleyGB, CameronJL.The role of oxygen-derived free radicals in the pathogenesis of acute pancreatitis.Ann Surg1984;200:405–13.
25.
SanfeyH, BulkleyGB, CameronJL.The pathogenesis of acute pancreatitis: The source and role of oxygen-derived free radicals in three different experimental models.Ann Surg1985;201:633–9.
26.
WarshawAL, O'HaraPJ.Susceptibility of the pancreas to ischemic injury in shock.Ann Surg1978;188:197–201.
27.
KlarE, MessmerK, WarshawAL, HerfarthC.Pancreatic ischaemia in experimental acute pancreatitis: Mechanism, significance and therapy.Br J Surg1990;77:1205–10.