Rare histologic variants of esophageal cancer account for about 5% of cases. As its name suggests, polypoid spindle cell carcinoma of the esophagus (carcinosarcoma, pseudosarcoma) is comprised of both epithelial and spindle cell elements. The nomenclature reflects both the historical controversy over the lesion's cell of origin as well as its characteristic fungating intraluminal growth pattern. The authors report a case of polypoid spindle cell carcinoma of the esophagus that was preoperatively diagnosed as a visceral sarcoma.
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References
1.
JemalA., MurrayT., SamuelsA.Cancer statistics, 2003.CA Cancer J Clin2003; 53: 5–26.
2.
DalyJ.M., FryW.A., LittleA.G.Esophageal cancer: Results of an American College of Surgeons Patient Care Evaluation Study.J Am Coll Surg2000; 190: 562–72.
3.
BrownL.M., DevesaS.S.Epidemiologic trends in esophageal and gastric cancer in the United States.Surg Oncol Clin North Am2002; 11: 235–56.
StoutA.P., HumphreysG.H., RottembergL.A.A case of carcinosarcoma of the esophagus.AJR Am J Roentgenol1949; 61: 461.
7.
IyomasaS., KatoH., TachimoriY.Carcinosarcoma of the esophagus: A twenty-case study.Jpn J Clin Oncol1990; 20: 99–106.
8.
NatsugoeS., MatsushitaY., ChumanY.So-called carcinosarcoma of the esophagus: A clinicopathologic, immunohistochemical and DNA flow-cytometric analysis of 6 cases.Oncology1999; 57: 29–35.
9.
IasconeC., BarrecaM.Carcinosarcoma and pseudosarcoma of the esophagus: Two names, one disease—Comprehensive review of the literature.World J Surg1999; 23: 153–7.
10.
TalbertJ.L., CantrellJ.R.Clinical and pathologic characteristics of carcinosarcoma of the esophagus.J Thorac Cardiovasc Surg1963; 45: 1–12.
BossetJ.F., GignouxM., TribouletJ.P.Chemoradiotherapy followed by surgery compared with surgery alone in squamous-cell cancer of the esophagus.N Engl J Med1997; 337: 161–7.
