Granulocytic sarcoma is a rare extramedullary soft-tissue tumor of granulocytic lineage with an incidence of 3 to 5 per cent in patients with acute myelogenous leukemia. The most common sites of involvement are bone, soft tissue, lymph nodes, and skin. Here we report three unusual cases of granulocytic sarcoma involving the gastrointestinal tract that required surgical intervention.
Get full access to this article
View all access options for this article.
References
1.
KingA.A case of chloroma.Monthly J Med1853;17:97.
2.
MussHB, MaloneyWC.Chloroma and other myeloblastic tumors.Blood1973;42:721–8.
3.
NeimanRS, BarcosM, BerardC, . Granulocytic sarcoma: A clinicopathologic study of 61 biopsy cases.Cancer1981; 48:1426–37.
4.
MeisJM, ButlerJJ, OsborneBM, ManningJT.Granulocytic sarcoma in nonleukemic patients.Cancer1986;58:2697–709.
5.
PriebeWM, SenecalFM.Gastric chloroma associated with upper gastrointestinal tract bleeding.Gastrointest Endosc1991;37:482–4.
6.
CorpechotC, LemannM, BrocheriouI, . Granulocytic sarcoma of the jejunum: A rare cause of small bowel obstruction.Am J Gastroenterol1998;93:2586–8.
7.
KocY, MillerKB, SchenkeinDP, . Extramedullary tumors of myeloid blasts in adults as a pattern of relapse following allogeneic bone marrow transplantation.Cancer1999;85:608–15.
8.
SzomorA, PasswegJR, TichelliA, . Myeloid leukemia and myelodysplastic syndrome relapsing as granulocytic sarcoma after allogeneic bone marrow transplantation.Ann Hematol1997; 75:239–41.
9.
BekassyA, HermansJ, GorinNC, GratwohlA.Granulocytic sarcoma after allogeneic bone marrow transplantation: A retrospective European multicenter survey.Bone Marrow Transplant1996;17:801–8.