Acupuncture Needle Sensation: The Emerging Evidence

Bovey M. Deqi. J Chin Med 2006;81:18–29.

Kong J , Gollub R , Huang T , Acupuncture de qi, from qualitative history to quantitative measurement. J Altern Complement Med 2007;13:1059–70.

White A , Cummings M , Barlas P , Defining an adequate dose of acupuncture using a neurophysiological approach – a narrative review of the literature. Acupunct Med 2008;26:111–20.

Benham A , Johnson MI . Could acupuncture needle sensation be a predictor of analgesic response. Acupunct Med 2009;27:65–7.

White P , Prescott P , Lewith G. Does needling sensation (de qi) affect treatment outcome in pain? Analysis of data from a larger single-blind, randomised controlled trial. Acupunct Med 2010;28:114–19.

Takeda W , Wessel J. Acupuncture for the treatment of pain of osteoarthritic knees. Arthritis Care Res 1994;7:118–22.

Berman BM , Lao L , Langenberg P , Effectiveness of acupuncture as adjunctive therapy in osteoarthritis of the knee: a randomized, controlled trial. Ann Intern Med 2004;141:901–10.

Witt C , Brinkhaus B , Jena S , Acupuncture in patients with osteoarthritis of the knee: a randomised trial. Lancet 2005;366:136–43.

Vas J , Perea-Milla E , Méndez C , Efficacy and safety of acupuncture for chronic uncomplicated neck pain: a randomised controlled study. Pain 2006;126:245–55.

Scharf HP , Mansmann U , Streitberger K , Acupuncture and knee osteoarthritis: a three-armed randomized trial. Ann Intern Med 2006;145:12–20.

Haake M , Müller HH , Schade-Brittinger C , German Acupuncture Trials (GERAC) for chronic low back pain: randomized, multicenter, blinded, parallel-group trial with 3 groups. Arch Intern Med 2007;167:1892–8.

Moore RA , Moore OA , Derry S , Responder analysis for pain relief and numbers needed to treat in a meta-analysis of etoricoxib osteoarthritis trials: bridging a gap between clinical trials and clinical practice. Ann Rheum Dis 2010;69:374–9.

MacPherson H , Asghar A. Acupuncture needle sensations associated with De Qi: a classification based on experts’ ratings. J Altern Complement Med 2006;12:633–7.

Asghar AU , Green G , Lythgoe MF , Acupuncture needling sensation: the neural correlates of deqi using fMRI. Brain Res 2010;1315:111–18.

Fang J , Jin Z , Wang Y , The salient characteristics of the central effects of acupuncture needling: limbic-paralimbic-neocortical network modulation. Hum Brain Mapp 2009;30:1196–206.

Hui KK , Liu J , Marina O , The integrated response of the human cerebro-cerebellar and limbic systems to acupuncture stimulation at ST 36 as evidenced by fMRI. Neuroimage 2005;27:479–96.

Hui KK , Nixon EE , Vangel MG , Characterization of the “deqi” response in acupuncture. BMC Complement Altern Med 2007;7:33.

Napadow V , Makris N , Liu J , Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI. Hum Brain Mapp 2005;24:193–205.

Lewith GT , White PJ , Pariente J. Investigating acupuncture using brain imaging techniques: the current state of play. Evid Based Complement Alternat Med 2005;2:315–19.

Yin CS , Park HJ , Kim SY , Electroencephalogram changes according to the subjective acupuncture sensation. Neurol Res 2010;32(Suppl 1):31–6.

Langevin HM , Bouffard NA , Badger GJ , Subcutaneous tissue fibroblast cytoskeletal remodeling induced by acupuncture: evidence for a mechanotransduction-based mechanism. J Cell Physiol 2006;207:767–74.

Langevin HM , Bouffard NA , Churchill DL , Connective tissue fibroblast response to acupuncture: dose-dependent effect of bidirectional needle rotation. J Altern Complement Med 2007;13:355–60.

Streitberger K , Eichenberger U , Schneider A , Ultrasound measurements of the distance between acupuncture needle tip at P6 and the median nerve. J Altern Complement Med 2007;13:585–91.

Kessler J , Streitberger K. Perforation of the median nerve with an acupuncture needle guided by ultrasound. Acupunct Med 2008;26:231–3.

Benham A , Phillips G , Johnson MI . An experimental study on the self-report of acupuncture needle sensation during deep needling with bi-directional rotation. Acupunct Med 2010;28:16–20.

Langevin HM , Churchill DL , Cipolla MJ . Mechanical signaling through connective tissue: a mechanism for the therapeutic effect of acupuncture. FASEB J 2001;15:2275–82.

Shanghai College of TCM. Morphological correlates of acupuncture sensations at human somatic acupoints. In. Selections from clinical and basic research on acupuncture analgesia. Shanghai: Shanghai Publishing House, 1977:205–9.

Wang KM , Yao SM , Xian YL , A study on the receptive field of acupoints and the relationship between characteristics of needling sensation and groups of afferent fibres. Sci Sin 1985;28: 963–71.

Sandkühler J. Long-lasting analgesia following TENS and acupuncture: spinal mechanisms beyond gate control. In: Devor M , Rowbotham MC , Wiesenfeld-Hallin Z , eds. Progress in pain research and management. Vol 16. Seattle, Washington, USA: IASP Press, 2000:359–69.

Kong J , Fufa DT , Gerber AJ , Psychophysical outcomes from a randomized pilot study of manual, electro, and sham acupuncture treatment on experimentally induced thermal pain. J Pain 2005;6:55–64.

Brown L , Holmes M , Jones A. The application of transcuutaneous electrical nerve stimulation to acupuncture points (Acu-TENS) for pain relief: a discussion of efficacy and potential mechanisms. Phys Ther Rev 2009;14:93–103.