The National Institute of Neurological Disorders and Stroke rt-pa Stroke Study Group: Tissue plasminogen activator for acute ischemic stroke. N Engl J Med1995; 333: 1581–7.
HackeWAlbersGAl-RawiY. The desmoteplase in acute ischemic stroke trial (DIAS): A phase II MRI-based 9–hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke2005; 36: 66–73.
6.
AlbersGWThijsVNWechslerL. Magnetic resonance imaging profiles predict clinical response to early reperfusion: The diffusion and perfusion imaging evaluation for understanding stroke evolution (defuse) study. Ann Neurol2006; 60: 508–17.
7.
BarberPADavisSMDarbyDG. Absent middle cerebral artery flow predicts the presence and evolution of the ischemic penumbra. Neurology1999; 52: 1125–32.
8.
ParsonsMWBarberPAChalkJ. Diffusion- and perfusion-weighted MRI response to thrombolysis in stroke. Ann Neurol2002; 51: 28–37.
9.
FurlanAJEydingDAlbersGW. Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): Evidence of safety and efficacy 3 to 9 hours after stroke onset. Stroke2006; 37: 1227–31.