A Subtle Historical Clue Unlocks a Contact Puzzle

Aoki J . Allergic contact dermatitis due to eye drops. Their clinical features and the patch test results. Nihon Ika Daigaku Zasshi, 1997; 64:232–237.

Aschenbeck KA , Warshaw EM . Periorbital allergic contact dermatitis due to ketotifen. Dermat Contact Atopic Occup Drug, 2017; 28:164–165.

Smets K , Werbrouck J , Goossens A , et al. Sensitization from ketotifen fumarate in eye drops presenting as chronic conjunctivitis. Contact Dermatitis, 2017; 76:124–126.

Niizeki H , Inamoto N , Nakamura K , et al. Contact dermatitis from ketotifen fumarate eyedrops. Contact Dermatitis, 1994; 31:266.

Grant SM , Goa KL , Fitton A , et al. Ketotifen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in asthma and allergic disorders. Drugs, 1990; 40:412–448.