In this article, we outline GP management of chronic fatigue syndrome (CFS), the condition also known colloquially in the UK as ‘ME’. The paper is based on National Institute for Health and Clinical Excellence (NICE) guidelines and also incorporates evidence-based strategies available to specialist services. GPs are well placed to make an early diagnosis of CFS and give patients helpful advice to manage their fatigue, hopefully avoiding multiple inappropriate referrals to specialist medical clinics.
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