Insulin therapy for people with type 1 diabetes is life saving and without insulin the condition is terminal. Insulin treatment is also needed in a significant number of people with type 2 diabetes to optimize glycaemic control. As more people with diabetes are now being managed exclusively in primary care, GPs and those training to become GPs need to have an understanding of insulin and its use in type 1 and type 2 diabetes.
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References
1.
DaviesM., StormsF., ShutlerS., Bianchi-BiscayM., GomisR.Improvement of glycemic control in subjects with poorly controlled type 2 diabetes: comparison of two treatment algorithms using insulin glargine. Diabetes Care (2005) 28: p. 1282–8 Accessed via care. diabetesjournals.org/content/28/6/1282.full.pdf+html [date last accessed 04.08.2009]
2.
GadsbyR.Using insulin earlier in the treatment of type 2 diabetes. British Journal of Diabetes and Vascular Disease (2003) 3: p. 119–22 Accessed via dvd.sagepub.com/cgi/reprint/3/2/119 [date last accessed 04.08.2009]
3.
HamannA., MatthaeiS., RosakC., SilvestreL.A randomized clinical trial comparing breakfast, dinner or bedtime administration of insulin glargine in patients with type 1 diabetes. Diabetes Care (2003) 26: p. 1738–44 Accessed via care.diabetesjournals.org/content/26/6/1738.full.pdf+html [date last accessed 04.08.2009]
4.
NICEClinical Guideline 15. Type 1 diabetes: diagnosis and management of type 1 diabetes in children, young people and adults (2004) Accessed via www.nice.org.uk/nicemedia/pdf/CG015NICEguideline.pdf [date last accessed 04.08.2009]
OiknineR., BernbaumM., MooradianA.D.A critical appraisal of the role of insulin analogues in the management of diabetes mellitus. Drugs (2005) 65 (3): p. 325–40
VagueP., SelamJ.L., SkeieS.Insulin detemir is associated with more predictable glycaemic control and reduced risk of hypoglycaemia than NPH insulin in patients with type 1 diabetes on a basal-bolus regime with premeal insulin aspart. Diabetes Care (2003) 26: p. 590–6 Accessed via care.diabetesjournals.org/content/26/3/590.full.pdf+html [date last accessed 04.08.2009]
