Hypercalcaemia has an incidence of approximately 1 in 500 in the community. It is most commonly caused by malignancy or hyperparathyroidism (90% of cases). Severe hypercalcaemia can be a medical emergency requiring hospital admission. This article covers the management of the common causes, gives a brief overview of the rare causes and provides a strategy with which to investigate hypercalcaemia of unknown aetiology.
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