Primary care is where most diagnoses of pituitary adenoma are made and pituitary adenomas are responsible for almost all pituitary problems. They typically present with a combination of symptoms of space occupation, hypopituitarism and/or inappropriate hormone secretion. As early diagnosis with optimal initial management and expert follow-up in the long-term help minimize morbidity, it could be argued that once conspicuous features of classical hormone-excess phenotypes such as acromegaly or Cushing's disease have emerged, diagnosis has been unduly delayed, even though the adenomas themselves are intrinsically benign.
