Anaphylaxis

Abstract

Anaphylaxis is a severe, systemic allergic reaction that is life threatening. Although less than 1% of those that suffer an anaphylactic attack die as a result of that attack, in the UK, there are approximately 20 deaths each year from anaphylaxis (one death per 3 million population). Risk of death is increased in those with pre-existing asthma, particularly, if the asthma is poorly controlled. Half of all fatalities due to anaphylaxis result from circulatory collapse (shock) and the remainder from respiratory failure (asphyxia). Prompt recognition and appropriate management saves lives.