Between 2 and 3% of the UK population experience depression in any year; a further 9% experience mixed anxiety and depression. The net costs of antidepressant medication in England alone in 2009 were just under £300 million. This article discusses the range of non-pharmacological treatments available to patients with depression and their use.
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References
1.
BordinE.S.The generalizability of the psychoanalytic concept of the working alliance. Psychotherapy: Theory, Research and Practice (1979) 16: p. 252–60
2.
CasacalendaN.PerryJ.C.LooperK.Remission in major depressive disorder: a comparison of pharmacotherapy, psychotherapy, and control conditions. American Journal of Psychiatry (2002) 159 (8): p. 1354–60
3.
ChristensenH.GriffithsK.M.JormA.F.Delivering interventions for depression by using the internet: randomised controlled trial. British Medical Journal (2004) 328 (7434): p. 265–9
4.
ChurchillR.HunotV.CorneyR.A systematic review of controlled trials of the effectiveness and cost-effectiveness of brief psychological treatments for depression. Health Technology Assessment (2001) 5 (35): p. 1–173. Accessed via www.hta.ac.uk/fullmono/mon535.pdf [date last accessed 30.1.2011]
5.
CoelhoH.F.CanterP.H.ErnstE.Mindfulness-based cognitive therapy: evaluating current evidence and informing future research. Journal of Consulting and Clinical Psychology (2007) 75 (6): p. 1000–5
6.
CuijpersP.van StratenA.SmitF.Psychological treatment of late-life depression: a meta-analysis of randomized controlled trials. International Journal of Geriatric Psychiatry (2006) 21 (12): p. 1139–49
7.
CuijpersP.van StratenA.WarmerdamL.Behavioral activation treatments of depression: a meta-analysis. Clinical Psychology Review (2007a) 27 (3): p. 318–26
8.
CuijpersP.van StratenA.WarmerdamL.Problem solving therapies for depression: a meta-analysis. European Psychiatry (2007b) 22 (1): p. 9–15
9.
CuijpersP.van StratenA.van OppenP.. Are psychological and pharmacologic interventions equally effective in the treatment of adult depressive disorders? A meta-analysis of comparative studies. Journal of Clinical Psychiatry (2008) 9: p. 1675–85
10.
de MelloM.F.de JesusMari, J.BacaltchukJ.VerdeliH.NeugebauerR.A systematic review of research findings on the efficacy of interpersonal therapy for depressive disorders. European Archives of Psychiatry and Clinical Neurosciences (2005) 255 (2): p. 75–82
HensleyP.L.NadigaD.UhlenhuthE.H.Long-term effectiveness of cognitive therapy in major depressive disorder. Depression and Anxiety (2004) 20 (1): p. 1–7
13.
HollinghurstS.KesslerD.PetersT.J.GunnellD.Opportunity cost of antidepressant prescribing in England: analysis of routine data. British Medical Journal (2005) 330 (7505): p. 999–1000
KaltenthalerE.BrazierJ.De NigrisE.Computerised cognitive behaviour therapy for depression and anxiety update: a systematic review and economic evaluation. Health Technology Assessment (2006) 10 (33): p. 1–168. Accessed via www.hta.ac.uk/pdfexecs/summ1033.pdf [date last accessed 30.1.2011]
16.
LarsonE.B.YaoY.Clinical empathy as emotional labour in the patient-physician relationship. Journal of the American Medical Association (2005) 293: p. 1100–6
17.
MartinD.J.GarskeJ.P.DavisM.K.Relation of the therapeutic alliance with outcome and other variables: a meta-analytic review. Journal of Consulting and Clinical Psychology (2000) 68: p. 438–50
18.
McLeanJ.MaxwellM.PlattS.HarrisF.JepsonR.Risk and protective factors for suicide and suicidal behaviour: a literature review (2008) Accessed via www.scotland.gov.uk/Publications/2008/11/28141444/0 [date last accessed 8.2.2011]
19.
MeadG.E.MorleyW.CampbellP.GreigC.A.McMurdoM.LawlorD.A.Exercise for depression. Cochrane Database of Systematic Reviews (2009) Issue 3. Art. No.: CD004366. DOI: 10.1002/14651858. CD004366.pub4
20.
MeadN.LesterH.Chew-GrahamC.GaskL.Effects of befriending on depressive symptoms and distress: systematic review and meta-analysis. British Journal of Psychiatry (2010) 196: p. 96–101
21.
Mental Health Foundation. Be mindful report (2010)
22.
MooreM.YuenH.DunnN.MulleeM.MaskellJ.KendrickT.Explaining the rise in antidepressant prescribing: a descriptive study using the general practice research database. British Medical Journal (2009) 339: p. b3999
23.
MorrisonJ.AndersonM-J.SuttonM.Factors influencing variation in prescribing of antidepressants by general practice in Scotland. British Journal of General Practice (2008) 59 (559): p. e25–31
24.
Mynors-WallisL.M.GathD.H.DayA.BakerF.Randomised controlled trial of problem solving treatment, antidepressant medication, and combined treatment for major depression in primary care. British Medical Journal (2000) 320 (7226): p. 26–30
PinquartM.DubersteinP.R.LynessJ.M.Treatments for later-life depressive conditions: a meta-analytic comparison of pharmacotherapy and psychotherapy. American Journal of Psychiatry (2006) 163 (9): p. 1493–501
28.
PrinsM.A.VerhaakP.F.M.BensingJ.M.van der MeerK.Health beliefs and perceived need for mental health care of anxiety and depression: the patients' perspective explored. Clinical Psychology Review (2008) 28: p. 1038–58
SIGN. Guideline number 114: non-pharmaceutical management of depression in adults: a national clinical guideline. (2010) Accessed via www.sign.ac.uk/pdf/sign114.pdf [date last accessed 30.1.2011]