Abstract
Introduction:
Will attainment of good bellows/plantar flexion at ≤3 volts fare better in controlling overactive bladder symptoms than at >4 volts?
Methods:
Between September 2001 and September 2010, we performed a retrospective cohort review of patients who underwent Stages 1 and 2 sacral neuromodulation placement for medically recalcitrant overactive bladder symptoms. All patients had pre- and postoperative overactive bladder symptom voiding diary results undergo statistical multivariable analysis. Group 1 patients had one or more tine leads placed with excellent motor provocation at ≤3 volts while Group 2 at >4 volts.
Results:
Mean follow-up of Group 1 (≤3 volts) was 8.43 ± 5.22 years and that of Group 2 (>3 volts)] was 9.56 ± 4.89 years. Patients with one lead with bellows and plantar flexion at ≤3 volts performed markedly better with improvements to frequency q24 hours Group 1, 18.72 ± 6.32 to 9.89 ± 3.12, compared with Group 2, 17.82 ± 5.23 to 11.88 ± 4.56, p < 0.02] urgency q24 hours Group 1 [2.87 ± 1.22 to 1.08 ± 0.68 compared with Group 2 2.77 ± 1.38 to 1.89 ± 1.02, p < 0.01], urgency incontinence Group1, 1.55 ± 1.21 to 0.70 ± 0.41 compared with Group 2, 1.48 ± 0.97 to 1.20 ± 0.51, p < 0.01 and nocturia Group 1, 3.02 ± 1.52 to 1.78 ± 0.79, Group 2, 3.33 ± 1.89 to 2.88 ± 1.46 voids per night (p < 0.02). Baseline UDI-6 scores improved from Group 1, 32.8 ± 22.1 to 6.9 ± 10.2, versus Group 2, 30.4 ± 19.6 to 8.9 ± 4.5 (p < 0.001). Similarly, IIQ-7 scores improved from Group 1, 22.1 ± 19.8 to 2.4 ± 8.2, versus Group 2, 20.6 ± 16.4 to 5.5 ± 6.3 (p < 0.02).
Conclusions:
Attainment of good bellows and plantar flexion at ≤3 volts with one or more leads may portend better qualitative clinical results for overactive bladder symptoms in women.
No competing financial interests exist.
Runtime of video: 6 mins 40 secs
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