Abstract
Background:
There are limited studies on the severity of Crimean-Congo hemorrhagic fever (CCHF) in children. The study aimed to investigate the correlation between the severity scoring index (SSI) score and other laboratory parameters in children.
Materials and Methods:
Patients younger than 18 years of age who were diagnosed with CCHF in 2011–2022 were included in the study. The SSI score and laboratory parameters at the time of admission were taken into consideration.
Results:
At 12-year follow-up, 81 pediatric patients were diagnosed with CCHF. According to the SSI calculated at the time of admission, 59 (72.8%) patients were in the mild group and 22 (27.2%) patients were in the moderate group. According to Spearman's correlation analysis results, a positive correlation was found between the SSI score and c-reactive protein (CRP) (r = 0.737, p < 0.001), lactate dehydrogenase (r = 0.312, p = 0.010), alanine transaminase to lymphocyte ratio (r = 0.428, p < 0.001), neutrophil to lymphocyte ratio (r = 0.406, p < 0.001), and derived-neutrophil lymphocyte ratio (r = 0.389, p < 0.001). In addition, lymphocyte to c-reactive protein ratio (LCR) (r = −0.782, p < 0.001), lymphocyte count (r = −0.422, p < 0.001), and white blood cell (r = −0.250, p = 0.026) values were negatively correlated with the SSI.
Conclusions:
A strong correlation (r > 0.7) was found between LCR (r = −0.782) and CRP (r = 0.737) and the SSI.
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