We report a fatal case of Bartonella henselae bacteremic patient. He had negative serology and PCRs from whole blood and liquid culture; only ftsZ nested PCR was positive from the blood liquid culture. The isolate had positive PCRs. When considered, bartonellosis diagnosis can be still challenging because of technical limitations.
Get full access to this article
View all access options for this article.
References
1.
BreitschwerdtEB. Did Bartonella henselae contribute to the deaths of two veterinarians?. Parasit Vectors, 2015; 8:317.
2.
BreitschwerdtEB, MaggiRG, CadenasMB, DinizPP. A groundhog, a novel Bartonella sequence, and my father's death. Emerg Infect Dis, 2009; 15:2080–2086.
3.
DinizPP, MaggiRG, SchwartzDS, CadenasMB, et al.Canine bartonellosis: Serological and molecular prevalence in Brazil and evidence of co-infection with Bartonella henselae and Bartonella vinsonii subsp. berkhoffii. Vet Res, 2007; 38:697–710.
4.
DrummondMR, LaniaBG, DinizPP, GilioliR, et al.Improvement of Bartonella henselae DNA detection in cat blood samples by combining molecular and culture methods. J Clin Microbiol, 2018; 56:pii: e01732-17.
VelhoPE, PimentelV, Del NegroGM, OkayTSet al.Severe anemia, panserositis, and cryptogenic hepatitis in an HIV patient infected with Bartonella henselae. Ultrastruct Pathol, 2007; 31:373–377.
10.
WilsonIG. Inhibition and facilitation of nucleic acid amplification. Appl Environ Microbiol, 1997; 63:3741–3751.