Acalculous cholecystitis has been described in association with Q fever. We describe the first known case of Q fever cholecystitis diagnosed by polymerase chain reaction on gallbladder tissue. The presence of Coxiella burnetii genome in the diseased gallbladder tissue argues for direct involvement of the organism in the pathogenesis of Q fever cholecystitis.
BrothertonJ, WangH, SchafferA, QuinnHet al.Vaccine preventable diseases and vaccination coverage in Australia, 2003 to 2005. CDI, 2007; 31,Suppl:S1–S152.
3.
Gonzalez-DelgadoL, LopezLG, SantolariaPS, GarciaPDet al.Acalculous cholecystitis: an uncommon form of presentation of Q fever. Gastroenterol Hepatol, 2005; 28:232–236.
4.
HartzellJD, PengSW, Wood-MorrisRN, SarmientoDMet al.Atypical Q fever in US soldiers. Emerg Infect Dis, 2007; 13:1247–1249.
5.
IsaacsD, DonaldP.Brothers with fever and abdominal pain. Pediatr Infect Dis J, 1998; 17:665–666.
6.
KellyR, ByrnesD, TurnerJ.Acute, severe hepatitis due to Coxiella burnetii infection. Med J Aust, 1986; 144:151–155.
RolainJM, LepidiH, HarleJR, AllegreTet al.Acute acalculous cholecystitis associated with Q fever: report of seven cases and review of the literature. Eur J Clin Microbiol Infect Dis, 2003; 22:222–227.
10.
TurraM, ChangG, WhybrowD, HigginsGet al.Diagnosis of acute Q fever by PCR on sera during a recent outbreak in rural south Australia. Ann NY Acad Sci, 2006; 1078:566–569.
