Physical activity is important in the development of mental and physical well-being during childhood. We aimed to investigate physical activity levels among early pubertal youth presenting for gender-affirming care. Among 93 participants 8–14 years of age, who had physical activity level measured using the Physical Activity Questionnaire for Children (PAQ-C), participants designated male at birth had lower levels of physical activity than participants designated female at birth both before starting gonadotropin-releasing hormone analog treatment and during gender-affirming medical treatment (baseline PAQ-C scores 2.24±0.73 vs. 2.67±0.73, p=0.006).
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