Re: “Concurrent Milk Ingestion Decreases Absorption of Levothyroxine” by Chon et al . ( Thyroid 2018;28:454–457)

Chon DA , Reisman T , Weinreb JE , Hershman JM , Leung AM . 2018. Concurrent milk ingestion decreases absorption of levothyroxine. Thyroid, 28:454–457.

Hennessey JV . Limitations of current bioequivalence standards. In: Orloff DG , ed. Equivalence of Levothyroxine Sodium Products. Joint Public Meeting. Board Room of the National Transportation Safety Board, L'Enfant Plaza. U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Washington, DC, 2005, pp 64–75.

Guidance for Industry: Bioavailability and Bioequivalence Studies for Orally Administered Drug Products—General Considerations (Draft Guidance). U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). 2002 1-24. Available at: www.fda.gov/.../ApprovalApplications/AbbreviatedNewDrugApplicationANDAGenerics/UCM154838.pdf (accessed June 3, 2018 ).

Blakesley VA , Awni W , Locke C , Ludden T , Granneman GR , Braverman LE . 2004. Are bioequivalalence studies of levothyroxine sodium formulations in euthyroid volunteers reliable?. Thyroid, 14:191–200.