Time for Thyrotropin Releasing Hormone to Return to the United States of America

Duntas LH , Emerson CH . 2009. On the fortieth anniversary of thyrotropin-releasing hormone: the hormone that launched a new era. Thyroid, 19:1299–1301.

Thyrel^® TRH Temporarily Removed from MarketATA Public Health StatementJuly 24, 2002. www.thyroid.org/professionals/publications/statements/02_07_24_trh_stop.html.

Faglia G . 1998. The clinical impact of the thyrotropin-releasing hormone test. Thyroid, 8:903–908.

Atmaca H , Tanriverdi F , Gokce C , Unluhizarci K , Kelestimur F . 2007. Do we still need the TRH stimulation test? Thyroid, 17:529–533.

Rapaport R . 2000. Congenital hypothyroidism: expanding the spectrum. J Pediatr, 136:10–12.

Kugelman A , Riskin A , Bader D , Koren I . 2009. Pitfalls in screening programs for congenital hypothyroidism in premature newborns. Am J Perinatol, 26:383–385.

American Academy of Pediatrics. Rose SR Section on Endocrinology and Committee on Genetics, American Thyroid Association Brown RS . Public Health Committee, Lawson Wilkins Pediatric Endocrine Society. Foley T , Kaplowitz PB , Kaye CI , Sundararajan S , Varma SK . 2006. Update of newborn screening and therapy for congenital hypothyroidism. Pediatrics, 117:2290–2303.

Tylek-Lemanska D , Kumorowicz-Kopiec M , Starzyk J . 2005. Screening for congenital hypothyroidism: the value of retesting after four weeks in neonates with low and very low birth weight. J Med Screen, 12:166–169.

Rapaport R , Sills I , Patel U , Oppenheimer E , Skuza K , Horlick M , Goldstein S , Dimartino J , Saenger P . 1993. Thyrotropin-releasing hormone stimulation tests in infants. J Clin Endocrinol Metab, 77:889–894.

Daliva AL , Linder B , DiMartino-Nardi J , Saenger P . 2000. Three-year follow-up of borderline congenital hypothyroidism. J Pediatr, 136:53–56.

Siklar Z , Tezer H , Dallar Y , Tanyer G . 2002. Borderline congenital hypothyroidism in the neonatal period. J Pediatr Endocrinol Metab, 15:817–821.

Leonardi D , Polizzotti N , Carta A , Gelsomino R , Sava L , Vigneri R , Calaciura F . 2008. Longitudinal study of thyroid function in children with mild hyperthyrotropinemia at neonatal screening for congenital hypothyroidism. J Clin Endocrinol Metab, 93:2679–2685.

Tatsumi K , Miyai K , Amino N . 1998. Genetic basis of congenital hypothyroidism: abnormalities in the TSHbeta gene, the PIT1 gene, and the NIS gene. Clin Chem Lab Med, 36:659–662.

Park SM , Clifton-Bligh RJ , Betts P , Chatterjee VK . 2004. Congenital hypothyroidism and apparent athyreosis with compound heterozygosity or compound hypothyroidism with probable hemizygosity for inactivating mutations of the TSH receptor. Clin Endocrinol (Oxf), 60:220–227.

Narumi S , Muroya K , Abe Y , Yasui M , Asakura Y , Adachi M , Hasegawa T . 2009. TSHR mutations as a cause of congenital hypothyroidism in Japan: a population-based genetic epidemiology study. J Clin Endocrinol Metab, 94:1317–1323.

Kanda K , Mizuno H , Sugiyama Y , Imamine H , Togari H , Onigata K . 2006. Clinical significance of heterozygous carriers associated with compensated hypothyroidism in R450H, a common inactivating mutation of the thyrotropin receptor gene in Japanese. Endocrine, 30:383–388.

Maruo Y , Takahashi H , Soeda I , Nishikura N , Matsui K , Ota Y , Mimura Y , Mori A , Sato H , Takeuchi Y . 2008. Transient congenital hypothyroidism caused by biallelic mutations of the dual oxidase 2 gene in Japanese patients detected by a neonatal screening program. J Clin Endocrinol Metab, 93:4261–4267.

Moreno JC , Bikker H , Kempers MJ , van Trotsenburg AS , Baas F , de Vijlder JJ , Vulsma T , Ris-Stalpers C . 2002. Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism. N Engl J Med, 347:95–102.

van Tijn DA , de Vijlder JJ , Vulsma T . 2008. Role of the thyrotropin-releasing hormone stimulation test in diagnosis of congenital central hypothyroidism in infants. J Clin Endocrinol Metab, 93:410–419.

Divall SA , Wondisford FE . 2008. TRH testing in its infancy. J Clin Endocrinol Metab, 93:378–379.

Kempers MJ , Lanting CI , van Heijst AF , van Trotsenburg AS , Wiedijk BM , de Vijlder JJ , Vulsma T . 2006. Neonatal screening for congenital hypothyroidism based on thyroxine, thyrotropin, and thyroxine-binding globulin measurement: potentials and pitfalls. J Clin Endocrinol Metab, 91:3370–3376.

Jackson IM . 1998. The thyroid axis and depression. Thyroid, 8:951–956.

Amsterdam JD , Fava M , Maislin G , Rosenbaum J , Hornig-Rohan M . 1996. TRH stimulation test as a predictor of acute and long-term antidepressant response in major depression. J Affect Disord, 38:165–172.