Current Advances in the Use of Therapeutic Hypothermia

Badjatia N , Cremers S , Claassen J , et al. Serum glutamine and hospital-acquired infections after aneurysmal subarachnoid hemorrhage. Neurology, 2018; 91:e421–e426.

Bartlett E , Valenzuela T , Idris A , et al. Systematic review and meta-analysis of INTRAvascular temperature management versus surface cooling in COMATose patients resuscitated from cardiac arrest. Resuscitation, 2019 [Epub ahead of print]; DOI: 10.1016/j.resuscitation.2019.10.035.

Basto FM , Lyden P . Hypothermia in acute ischemic stroke therapy. Handb Clin Neurol, 2018; 157:823–837.

Chandrasekaran PN , Dezfulian C , Polderman KH . What is the right temperature to cool post-cardiac arrest patients?. Crit Care, 2015; 19:406.

Dumitrascu OM , Lamb J , Lyden PD . Still cooling after all these years: meta-analysis of pre-clinical trials of therapeutic hypothermia for acute ischemic stroke. J Cereb Blood Flow Metab, 2016; 36:1157–1164.

Gowda R , Jaffa M , Badjatia N . Thermoregulation in brain injury. Handb Clin Neurol, 2018; 157:789–797.

Khan I , Haymore J , Barnaba B , et al. Esophageal cooling device versus other temperature modulation devices for therapeutic normothermia in subarachnoid and intracranial hemorrhage. Ther Hypothermia Temp Manag, 2018; 8:53–58.

Kurz M , Lundbye J , Lyden PD . Clinical studies targeting stroke and in-hospital cardiac arrest. Ther Hypothermia Temp Manag, 2016; 6:6–8.

Kurz M , Polderman K , Brophy GM , et al. Unique uses of cooling strategies. Ther Hypothermia Temp Manag, 2019; 9:168–172.

Lamb JA , Rajput PS , Lyden PD . Novel method for inducing rapid, controllable therapeutic hypothermia in rats using a perivascular implanted closed-loop cooling circuit. J Neurosci Methods, 2016; 267:55–61.

Lundbye J , Hand H , Adams M , et al. Targeted temperature management in nursing care. Ther Hypothermia Temp Manag, 2017; 7:122–124.

Lyden P , Hemmen T , Grotta J , et al. Results of the ICTuS 2 trial (intravascular cooling in the treatment of Stroke 2). Stroke, 2016; 47:2888–2895.

Lyden PD , Lamb J , Kothari S , et al. Differential effects of hypothermia on neurovascular unit determine protective or toxic results: toward optimized therapeutic hypothermia. J Cereb Blood Flow Metab, 2019; 39:1693–1709.

Noyes AM , Lundbye JB . Managing the complications of mild therapeutic hypothermia in the cardiac arrest patient. J Intensive Care Med, 2015; 30:259–269.

Pergakis M , Badjatia N , Chaturvedi S , et al. BIIB093 (IV glibenclamide): an investigational compound for the prevention and treatment of severe cerebral edema. Expert Opin Investig Drugs, 2019; 28:1031–1040.

Polderman K , Lockhart K , Badjatia N . Temperature management in neurological and neurosurgical intensive care units. Ther Hypothermia Temp Manag, 2014; 4:62–66.

Polderman K , Lundbye J , Nichol G , et al. Therapeutic hypothermia in postcardiac arrest. Ther Hypothermia Temp Manag, 2019; 9:102–107.

Polderman KH , Varon J . Confusion around therapeutic temperature management hypothermia after in-hospital cardiac arrest?. Circulation, 2018; 137:219–221.

Sawyer KN , Mooney M , Norris G , et al. COOL-ARREST: results from a pilot multicenter, prospective, single-arm observational trial to assess intravascular temperature management in the treatment of cardiac arrest. Ther Hypothermia Temp Manag, 2019; 9:56–62.