Current Advances in the Use of Therapeutic Hypothermia

Bro-Jeppesen J , Annborn M , Hassager C , Wise MP , Pelosi P , Nielsen N , Erlinge D , Wanscher M , Friberg H , Kjaergaard J ; on behalf of the TTM Investigators. Hemodynamics and vasopressor support during targeted temperature management at 33°C versus 36°C after out-of-hospital cardiac arrest: a post hoc study of the Target Temperature Management trial. Crit Care Med, 2014. [Epub ahead of print]

Bro-Jeppesen J , Hassager C , Wanscher M , Østergaard M , Nielsen N , Erlinge D , Friberg H , Køber L , Kjaergaard J . Targeted temperature management at 33°C versus 36°C and impact on systemic vascular resistance and myocardial function after out-of-hospital cardiac arrest: a sub-study of the Target Temperature Management Trial. Circ Cardiovasc Interv, 2014; 7:663–672.

Erlinge D . A review of mild hypothermia as an adjunctive treatment for ST-elevation myocardial infarction. Ther Hypothermia Temp Manag, 2011; 1:129–141.

Erlinge D , Götberg M , Lang I , Holzer M , Noc M , Clemmensen P , Jensen U , Metzler B , James S , Bötker HE , Omerovic E , Engblom H , Carlsson M , Arheden H , Ostlund O , Wallentin L , Harnek J , Olivecrona GK . Rapid endovascular catheter core cooling combined with cold saline as an adjunct to percutaneous coronary intervention for the treatment of acute myocardial infarction. The CHILL-MI trial: a randomized controlled study of the use of central venous catheter core cooling combined with cold saline as an adjunct to percutaneous coronary intervention for the treatment of acute myocardial infarction. J Am Coll Cardiol, 2014; 63:1857–1865.

Götberg M , Olivecrona GK , Koul S , Carlsson M , Engblom H , Ugander M , van der Pals J , Algotsson L , Arheden H , Erlinge D . A pilot study of rapid cooling by cold saline and endovascular cooling before reperfusion in patients with ST-elevation myocardial infarction. Circ Cardiovasc Interv, 2010; 3:400–407.

Kander T , Brokopp J , Erlinge D , Lood C , Schött U . Temperature effects on haemostasis in whole blood from ticagrelor- and aspirin-treated patients with acute coronary syndrome. Scand J Clin Lab Invest, 2014; 3:1–9.

Kim F , Maynard C , Nichol G . Prehospital therapeutic hypothermia in patients with out-of-hospital cardiac arrest—reply. JAMA, 2014; 311:2233–2234.

Kim F , Nichol G , Maynard C , Hallstrom A , Kudenchuk PJ , Rea T , Copass MK , Carlbom D , Deem S , Longstreth WT Jr. , Olsufka M , Cobb LA . Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial. JAMA, 2014; 311:45–52.

Knight CJ , Keeble TR , Wilson S , Cooper J , Deaner A , Ranjadayalan K , Timmis AD . Short term prognosis of patients with acute coronary syndromes: the level of cardiac troponin T elevation corresponding to the “old” WHO definition of myocardial infarction. Heart, 2005; 91:373–374.

Kochanek PM , Erlinge D , Polderman KH , Windsor J . Developing cooling strategies targeting the heart in adults and children. Ther Hypothermia Temp Manag, 2012; 2:157–161.

McColl AJ , Keeble T , Hadjinikolaou L , Cohen A , Aitkenhead H , Glenville B , Richmond W . Plasma antioxidants: evidence for a protective role against reactive oxygen species following cardiac surgery. Ann Clin Biochem, 1998; 35:616–623.

Mikkelsen ME , Christie JD , Abella BS , Kerlin MP , Fuchs BD , Schweickert WD , Berg RA , Mosesso VN , Shofer FS , Gaieski DF . American Heart Association's Get With the Guidelines-Resuscitation Investigators. Use of therapeutic hypothermia after in-hospital cardiac arrest. Crit Care Med, 2013; 41:1385–1395.

Nichol G , Elrod JA , Becker LB . Treatment for out-of-hospital cardiac arrest: is the glass half empty or half full?. Circulation, 2014; 130:1844–1846.

Nishiyama C , Brown SP , May S , Iwami T , Koster RW , Beesems SG , Kuisma M , Salo A , Jacobs I , Finn J , Sterz F , Nürnberger A , Smith K , Morrison L , Olasveengen TM , Callaway CW , Shin SD , Gräsner JT , Daya M , Ma MH , Herlitz J , Strömsöe A , Aufderheide TP , Masterson S , Wang H , Christenson J , Stiell I , Davis D , Huszti E , Nichol G . Apples to apples or apples to oranges? International variation in reporting of process and outcome of care for out-of-hospital cardiac arrest. Resuscitation, 2014; 85:1599–1609.

Perkins GD , Jacobs IG , Nadkarni VM , Berg RA , Bhanji F , Biarent D , Bossaert LL , Brett SJ , Chamberlain D , de Caen AR , Deakin CD , Finn JC , Gräsner JT , Hazinski MF , Iwami T , Koster RW , Lim SH , Ma MH , McNally BF , Morley PT , Morrison LJ , Monsieurs KG , Montgomery W , Nichol G , Okada K , Ong ME , Travers AH , Nolan JP . Cardiac arrest and cardiopulmonary resuscitation outcome reports: update of the Utstein resuscitation registry templates for out-of-hospital cardiac arrest. Resuscitation, 2014. [Epub ahead of print]; doi: 10.1016/j.resuscitation.2014.11.002.

Ruiz P , Rezaienia MA , Rahideh A , Keeble TR , Rothman MT , Korakianitis T . In vitro cardiovascular system emulator (bioreactor) for the simulation of normal and diseased conditions with and without mechanical circulatory support. Artif Organs, 2013; 37:549–560.