Managing Hypothermia in Cardiac Arrest and Rewarming

Athar MK , Levine JM . Treatment options for cerebral vasospasm in aneurysmal subarachnoid hemorrhage. Neurotherapeutics., 2012; 9:37–43.

Cairns CB , Maier RV , Adeoye O , Baptiste D , Barsan WG , Blackbourne L , Burd R , Carpenter C , Chang D , Cioffi W , Cornwell E , Dean JM , Dyer C , Jaffe D , Manley G , Meurer WJ , Neumar R , Silbergleit R , Stevens M , Wang M , Weiner D , Wright D , Roundtable External Participants and Roundtable Steering Committee and Federal Participants. NIH Roundtable on Emergency Trauma Research. Ann Emerg Med, 2010; 56:538–550.

Hindman BJ , Bayman EO , Pfisterer WK , Torner JC , Todd MM , IHAST Investigators. No association between intraoperative hypothermia or supplemental protective drug and neurologic outcomes in patients undergoing temporary clipping during cerebral aneurysm surgery: findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial. Anesthesiology, 2010; 112:86–101.

Holena DN , Tolstoy NS , Mills AM , Fox AD , Levine JM . Therapeutic hypothermia for treatment of intractable intracranial hypertension after liver transplantation. Am J Crit Care, 2012; 21:72–75.

Kim MN , Edlow BL , Durduran T , Frangos S , Mesquita RC , Levine JM , Greenberg JH , Yodh AG , Detre JA . Continuous Optical Monitoring of Cerebral Hemodynamics During Head-of-Bed Manipulation in Brain-Injured Adults. Neurocrit Care. May 8, 2013 [Epub ahead of print]; 10.1007/s12028-013-9849-7.

Meurer WJ , Lewis RJ , Tagle D , Fetters MD , Legocki L , Berry S , Connor J , Durkalski V , Elm J , Zhao W , Frederiksen S , Silbergleit R , Palesch Y , Berry DA , Barsan WG . (2012). An overview of the adaptive designs accelerating promising trials into treatments (ADAPT-IT) project. Ann Emerg Med., 60:451–457.

Nguyen HP , Zaroff JG , Bayman EO , Gelb AW , Todd MM , Hindman BJ , IHAST-MIDS and IHAST Investigators. (2010). Perioperative hypothermia (33 degrees C) does not increase the occurrence of cardiovascular events in patients undergoing cerebral aneurysm surgery: findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial. Anesthesiology, 2010; 13:327–342.

Oddo M , Levine JM , Kumar M , Iglesias K , Frangos S , Maloney-Wilensky E , Le Roux PD . Anemia and brain oxygen after severe traumatic brain injury. Intensive Care Med, 2012; 38:1497–1504.

Paulsen MJ , Haddock AJ , Silbergleit R , Meurer WJ , Macy ML , Haukoos JS , Sasson C . Empirical hospital and professional charges for patient care associated with out of hospital cardiac arrest before and after implementation of therapeutic hypothermia for comatose survivors. Resuscitation., 2002; 83:1265–1270.

Sanborn MR , Thom SR , Bohman LE , Stein SC , Levine JM , Milovanova T , Maloney-Wilensky E , Frangos S , Kumar MA . Temporal dynamics of microparticle elevation following subarachnoid hemorrhage. J Neurosurg, 2012; 117:579–586.

Scott PA , Meurer WJ , Frederiksen SM , Kalbfleisch JD , Xu Z , Haan MN , Silbergleit R , Morgenstern LB , INSTINCT Investigators. A multilevel intervention to increase community hospital use of alteplase for acute stroke (INSTINCT): a cluster-randomised controlled trial. Lancet Neurol, 2013; 12:139–148.

Silbergleit R , Biros MH , Harney D , Dickert N , Baren J , NETT Investigators. Implementation of the exception from informed consent regulations in a large multicenter emergency clinical trials network: the RAMPART experience. Acad Emerg Med, 2012; 19:448–454.

Siman R , Giovannone N , Toraskar N , Frangos S , Stein SC , Levine JM , Kumar MA . Evidence that a panel of neurodegeneration biomarkers predicts vasospasm, infarction, and outcome in aneurysmal subarachnoid hemorrhage. PLoS One, 2011; 6:e28938.

Whitmore RG , Thawani JP , Grady MS , Levine JM , Sanborn MR , Stein SC . Is aggressive treatment of traumatic brain injury cost-effective?. J Neurosurg, 2012; 116:1106–1113.