This article has been officially retracted from the Journal
Get full access to this article
View all access options for this article.
References
1.
BryderD., RossiD.J., WeissmanI.L.Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol, 169:338. 2006.
2.
AsaharaT., KawamotoA.Endothelial progenitor cells for postnatal vasculogenesis. Am J Physiol Cell Physiol, 287:C572. 2004.
3.
LindvallO., KokaiaZ., Martinez-SerranoA.Stem cell therapy for human neurodegenerative disorders-how to make it work. Nat Med, 10,Suppl:S42. 2004.
4.
Bonner-WeirS., WeirG.C.New sources of pancreatic beta-cells. Nat Biotechnol, 23:857. 2005.
5.
MimeaultM., BatraS.K.Concise review: recent advances on the significance of stem cells in tissue regeneration and cancer therapies. Stem Cells, 24:2319. 2006.
6.
ArbabA.S., YocumG.T., KalishH., JordanE.K., AndersonS.A., KhakooA.Y.et al.Efficient magnetic cell labeling with protamine sulfate complexed to ferumoxides for cellular MRI. Blood, 104:1217. 2004.
7.
BaumjohannD., HessA., BudinskyL., BruneK., SchulerG., LutzM.B.In vivo magnetic resonance imaging of dendritic cell migration into the draining lymph nodes of mice. Eur J Immunol, 36:2544. 2006.
8.
BaumjohannD., LutzM.B.Non-invasive imaging of dendritic cell migration in vivo. Immunobiology, 211:587. 2006.
9.
KamalyN., KalberT., AhmadA., OliverM.H., SoP.W., HerlihyA.H.et al.Bimodal paramagnetic and fluorescent liposomes for cellular and tumor magnetic resonance imaging. Bioconjug Chem, 19:118. 2008.
10.
AimeS., BargeA., CabellaC., CrichS.G., GianolioE.Targeting cells with MR imaging probes based on paramagnetic Gd(III) chelates. Curr Pharm Biotechnol, 5:509. 2004.
11.
AndersonS.A., LeeK.K., FrankJ.A.Gadolinium-fullerenol as a paramagnetic contrast agent for cellular imaging. Invest Radiol, 41:332. 2006.
12.
BogaardsA., SterenborgH.J., TrachtenbergJ., WilsonB.C., LilgeL.In vivo quantification of fluorescent molecular markers in real-time by ratio imaging for diagnostic screening and image-guided surgery. Lasers Surg Med, 39:605. 2007.
13.
BhaumikS., GambhirS.S.Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc Natl Acad Sci USA, 99:377. 2002.
14.
BulteJ.W., KraitchmanD.L.Iron oxide MR contrast agents for molecular and cellular imaging. NMR Biomed, 17:484. 2004.
15.
BulteJ.W., ArbabA.S., DouglasT., FrankJ.A.Preparation of magnetically labeled cells for cell tracking by magnetic resonance imaging. Methods Enzymol, 386:275. 2004.
16.
SheikhA.Y., LinS.A., CaoF., CaoY., van der BogtK.E., ChuP.et al.Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells, 25:2677. 2007.
ModoM.Understanding stem cell-mediated brain repair through neuroimaging. Curr Stem Cell Res Ther, 1:55. 2006.
19.
WalczakP., ZhangJ., GiladA.A., KedziorekD.A., Ruiz-CabelloJ., YoungR.G.et al.Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke, 39:1569. 2008.
20.
HeynC., RonaldJ.A., MackenzieL.T., MacDonaldI.C., ChambersA.F., RuttB.K.et al.In vivo magnetic resonance imaging of single cells in mouse brain with optical validation. Magn Reson Med, 55:23. 2006.
21.
HeynC., RonaldJ.A., RamadanS.S., SnirJ.A., BarryA.M., MacKenzieL.T.et al.In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain. Magn Reson Med, 56:1001. 2006.
22.
KimD., HongK.S., SongJ.The present status of cell tracking methods in animal models using magnetic resonance imaging technology. Mol Cells, 23:132. 2007.
23.
GuzmanR., UchidaN., BlissT.M., HeD., ChristophersonK.K., StellwagenD.et al.Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc Natl Acad Sci USA, 104:10211. 2007.
24.
AraiT., KofidisT., BulteJ.W., de BruinJ., VenookR.D., BerryG.J.et al.Dual in vivo magnetic resonance evaluation of magnetically labeled mouse embryonic stem cells and cardiac function at 1.5 t. Magn Reson Med, 55:203. 2006.
25.
KraitchmanD.L., TatsumiM., GilsonW.D., IshimoriT., KedziorekD., WalczakP.et al.Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation, 112:1451. 2005.
26.
ArbabA.S., LiuW., FrankJ.A.Cellular magnetic resonance imaging: current status and future prospects. Expert Rev Med Devices, 3:427. 2006.
27.
HoehnM., KustermannE., BlunkJ., WiedermannD., TrappT., WeckerS.et al.Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci USA, 99:16267. 2002.
28.
LewinJ.S., NourS.G., DuerkJ.L.Magnetic resonance image-guided biopsy and aspiration. Top Magn Reson Imaging, 11:173. 2000.
29.
ZhuJ., ZhouL., XingWuF.Tracking neural stem cells in patients with brain trauma. N Engl J Med, 355:2376. 2006.
30.
Daldrup-LinkH., RudeliusM., OostendorpR., SettlesM., PiontekG., MetzS.et al.Targeting of hematopoietic progenitor cells with MR contrast agents. Radiology, 228:760. 2003.
31.
JendelováP., HerynekV., UrdzíkováL., GlogarováK., KroupováJ., AnderssonB.et al.Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord. J Neurosci Res, 76:232. 2004.
32.
HillJ., DickA., RamanV., ThompsonR., YuZ., HindsK.et al.Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells. Circulation, 108:1009. 2003.
33.
TerrovitisJ., BulteJ., SarvananthanS., CroweL., SarathchandraP., BattenP.et al.Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells seeded on collagen scaffolds-relevance to tissue engineering. Tissue Eng, 12:2765. 2006.
34.
NelsonG., RohJ., MirenskyT., WangY., YiT., TellidesG.et al.Initial evaluation of the use of USPIO cell labeling and noninvasive MR monitoring of human tissue-engineered vascular grafts in vivo. FASEB J, 22:3888. 2008.
35.
de VriesI.J., LesterhuisW.J., BarentszJ.O., VerdijkP., van KriekenJ.H., BoermanO.C.et al.Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol, 23:1407. 2005.
36.
ArbabA.S., BashawL.A., MillerB.R., JordanE.K., LewisB.K., KalishH.et al.Characterization of biophysical and metabolic properties of cells labeled with superparamagnetic iron oxide nanoparticles and transfection agent for cellular MR imaging. Radiology, 229:838. 2003.
37.
HarisinghaniM.G., BarentszJ., HahnP.F., DesernoW.M., TabatabaeiS., van de KaaC.H.et al.Noninvasive detection of clinically occult lymph-node metastases in prostate cancer. N Engl J Med, 348:2491. 2003.
38.
RaynalI., PrigentP., PeyramaureS., NajidA., RebuzziC., CorotC.Macrophage endocytosis of superparamagnetic iron oxide nanoparticles: mechanisms and comparison of ferumoxides and ferumoxtran-10. Invest Radiol, 39:56. 2004.
39.
BeckerW., MellerJ.The role of nuclear medicine in infection and inflammation. Lancet Infect Dis, 1:326. 2001.
40.
EggertA.A., SchreursM.W., BoermanO.C., OyenW.J., de BoerA.J., PuntC.J.et al.Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration. Cancer Res, 59:3340. 1999.
41.
BohnenN.I., CharronM., ReyesJ., RubinsteinW., StromS.C., SwansonD.et al.Use of indium-111-labeled hepatocytes to determine the biodistribution of transplanted hepatocytes through portal vein infusion. Clin Nucl Med, 25:447. 2000.
42.
ChinB.B., NakamotoY., BulteJ.W., PittengerM.F., WahlR., KraitchmanD.L.111In oxine labelled mesenchymal stem cell SPECT after intravenous administration in myocardial infarction. Nucl Med Commun, 24:1149. 2003.
43.
KircherM.F., GrimmJ., SwirskiF.K., LibbyP., GersztenR.E., AllportJ.R.et al.Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions. Circulation, 117:388. 2008.
44.
ZhangY., ThornS., DaSilvaJ., LamoureuxM., DeKempR., BeanlandsR.et al.Collagen-based matrices improve the delivery of transplanted circulating progenitor cells: development and demonstration by ex vivo radionuclide cell labeling and in vivo tracking with positron-emission tomography. Circ Cardiovasc Imaging, 1:197. 2008.
45.
JonuleitH., Giesecke-TuettenbergA., TutingT., Thurner-SchulerB., StugeT.B., ParagnikL.et al.A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection. Int J Cancer, 93:243. 2001.
46.
DhodapkarM.V., SteinmanR.M., KrasovskyJ., MunzC., BhardwajN.Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J Exp Med, 193:233. 2001.
47.
De VriesI.J., KrooshoopD.J., ScharenborgN.M., LesterhuisW.J., DiepstraJ.H., Van MuijenG.N.et al.Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res, 63:12. 2003.
48.
MorseM.A., ColemanR.E., AkabaniG., NiehausN., ColemanD., LyerlyH.K.Migration of human dendritic cells after injection in patients with metastatic malignancies. Cancer Res, 59:56. 1999.
49.
QuillienV., MoisanA., CarsinA., LesimpleT., LefeuvreC., AdamskiH.et al.Biodistribution of radiolabelled human dendritic cells injected by various routes. Eur J Nucl Med Mol Imaging, 32:731. 2005.
50.
RidolfiR., RiccobonA., GalassiR., GiorgettiG., PetriniM., FiammenghiL.et al.Evaluation of in vivo labelled dendritic cell migration in cancer patients. J Transl Med, 2:27. 2004.
51.
BlockletD., ToungouzM., KissR., LambermontM., VeluT., DuriauD.et al.111In-oxine and 99mTc-HMPAO labelling of antigen-loaded dendritic cells: in vivo imaging and influence on motility and actin content. Eur J Nucl Med Mol Imaging, 30:440. 2003.
52.
NairS., McLaughlinC., WeizerA., SuZ., BoczkowskiD., DannullJ.et al.Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J Immunol, 171:6275. 2003.
53.
ThompsonM., WallD.M., HicksR.J., PrinceH.M.In vivo tracking for cell therapies. Q J Nucl Med Mol Imaging, 49:339. 2005.
54.
TrakatelliM., ToungouzM., BlockletD., DodooY., GordowerL., LaporteM.et al.A new dendritic cell vaccine generated with interleukin-3 and interferon-beta induces CD8+ T cell responses against NA17-A2 tumor peptide in melanoma patients. Cancer Immunol Immunother, 55:469. 2006.
55.
MackensenA., KrauseT., BlumU., UhrmeisterP., MertelsmannR., LindemannA.Homing of intravenously and intralymphatically injected human dendritic cells generated in vitro from CD34+ hematopoietic progenitor cells. Cancer Immunol Immunother, 48:118. 1999.
56.
VerdijkP., AarntzenE.H., LesterhuisW.J., BoullartA.C., KokE., van RossumM.M.et al.Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clin Cancer Res, 15:2531. 2009.
57.
ContagC.H., JenkinsD., ContagP.R., NegrinR.S.Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia, 2:41. 2000.
58.
WuJ.C., SundaresanG., IyerM., GambhirS.S.Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. Mol Ther, 4:297. 2001.
59.
SweeneyT.J., MailanderV., TuckerA.A., OlomuA.B., ZhangW., CaoY.et al.Visualizing the kinetics of tumor-cell clearance in living animals. Proc Natl Acad Sci USA, 96:12044. 1999.
60.
CostaG.L., SandoraM.R., NakajimaA., NguyenE.V., Taylor-EdwardsC., SlavinA.J.et al.Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit. J Immunol, 167:2379. 2001.
61.
MandlS., SchimmelpfennigC., EdingerM., NegrinR.S., ContagC.H.Understanding immune cell trafficking patterns via in vivo bioluminescence imaging. J Cell Biochem Suppl, 39:239. 2002.
62.
WangX., RosolM., GeS., PetersonD., McNamaraG., PollackH.et al.Dynamic tracking of human hematopoietic stem cell engraftment using in vivo bioluminescence imaging. Blood, 102:3478. 2003.
63.
CaoY.A., WagersA.J., BeilhackA., DusichJ., BachmannM.H., NegrinR.S.et al.Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci USA, 101:221. 2004.
64.
TianW., WangG., LuoS., DongX., FuX., TanW.et al.[Real time ex vivo detection and dynamic monitoring of in vivo expression of secreted luciferase gene injected by hydrodynamic method]Sheng Wu Gong Cheng Xue Bao, 25:1552. 2009.
65.
TogelF., YangY., ZhangP., HuZ., WestenfelderC.Bioluminescence imaging to monitor the in vivo distribution of administered mesenchymal stem cells in acute kidney injury. Am J Physiol Renal Physiol, 295:F315. 2008.
66.
BlumJ., TemenoffJ., ParkH., JansenJ., MikosA., BarryM.Development and characterization of enhanced green fluorescent protein and luciferase expressing cell line for non-destructive evaluation of tissue engineering constructs. Biomaterials, 25:5809. 2004.
67.
MiyoshiH., BlomerU., TakahashiM., GageF.H., VermaI.M.Development of a self-inactivating lentivirus vector. J Virol, 72:8150. 1998.
68.
OkadaS., IshiiK., YamaneJ., IwanamiA., IkegamiT., KatohH.et al.In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury. FASEB J, 19:1839. 2005.
69.
GeuzeR., PrinsH., OnerF., van der HelmY., SchuijffL., MartensA.et al.Luciferase labeling for multipotent stromal cell tracking in spinal fusion versus ectopic bone tissue engineering in mice, rats. Tissue Eng Part A, 2010Epub ahead of print].
70.
RiceB.W., CableM.D., NelsonM.B.In vivo imaging of light-emitting probes. J Biomed Opt, 6:432. 2001.
71.
JafferF., WeisslederR.Molecular imaging in the clinical arena. JAMA, 293:855. 2005.
72.
TungC., BredowS., MahmoodU., WeisslederR.Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging. Bioconjug Chem, 10:892. 1999.
73.
TungC., MahmoodU., BredowS., WeisslederR.In vivo imaging of proteolytic enzyme activity using a novel molecular reporter. Cancer Res, 60:4953. 2000.
74.
WeisslederR., TungC., MahmoodU., BogdanovA.J.In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol, 17:375. 1999.
75.
BremerC., TungC., WeisslederR.In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med, 7:743. 2001.
HjortnaesJ., GottliebD., FigueiredoJ., Melero-MartinJ., KohlerR., BischoffJ.et al.Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study. Tissue Eng Part C Methods, 16:597. 2010.
78.
JafferF., LibbyP., WeisslederR.Molecular and cellular imaging of atherosclerosis: emerging applications. J Am Coll Cardiol, 47:1328. 2006.
79.
NahrendorfM., SosnovikD., WeisslederR.MR-optical imaging of cardiovascular molecular targets. Basic Res Cardiol, 103:87. 2008.
80.
TungC.H., BredowS., MahmoodU., WeisslederR.Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging. Bioconjug Chem, 10:892. 1999.
81.
HjortnaesJ., ButcherJ., FigueiredoJ., RiccioM., KohlerR., KozloffK.et al.Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation. Eur Heart J, 31:1975. 2010.
82.
MichaletX., PinaudF.F., BentolilaL.A., TsayJ.M., DooseS., LiJ.J.et al.Quantum dots for live cells, in vivo imaging, and diagnostics. Science, 307:538. 2005.
83.
ShahB.S., ClarkP.A., MoioliE.K., StroscioM.A., MaoJ.J.Labeling of mesenchymal stem cells by bioconjugated quantum dots. Nano Lett, 7:3071. 2007.
84.
SlotkinJ.R., ChakrabartiL., DaiH.N., CarneyR.S., HirataT., BregmanB.S.et al.In vivo quantum dot labeling of mammalian stem and progenitor cells. Dev Dyn, 236:3393. 2007.
85.
ChakrabortyS.K., FitzpatrickJ.A., PhillippiJ.A., AndrekoS., WaggonerA.S., BruchezM.P.et al.Cholera toxin B conjugated quantum dots for live cell labeling. Nano Lett, 7:2618. 2007.
86.
ChenH.T.I., StroscioM., ChoM.Altered membrane dynamics of quantum dot-conjugated integrins during osteogenic differentiation of human bone marrow derived progenitor cells. Biophys J, 92:1399. 2007.
87.
HsiehS.C., WangF.F., LinC.S., ChenY.J., HungS.C., WangY.J.The inhibition of osteogenesis with human bone marrow mesenchymal stem cells by CdSe/ZnS quantum dot labels. Biomaterials, 27:1656. 2006.
88.
HsiehS.C., WangF.F., HungS.C., ChenY.J., WangY.J.The internalized CdSe/ZnS quantum dots impair the chondrogenesis of bone marrow mesenchymal stem cells. J Biomed Mater Res B Appl Biomater, 79:95. 2006.
89.
DubertretB., SkouridesP., NorrisD.J., NoireauxV., BrivanlouA.H., LibchaberA.In vivo imaging of quantum dots encapsulated in phospholipid micelles. Science, 298:1759. 2002.
90.
DupontK., SharmaK., StevensH., BoerckelJ., GarcíaA., GuldbergR.Human stem cell delivery for treatment of large segmental bone defects. Proc Natl Acad Sci USA, 107:3305. 2010.
91.
AshbridgeD.A.T.M., RiversM.L., MuccinoJ.C., O'DayP.A.Image optimization and analysis of synchrotron X-ray computed microtomography (CmT) data. Comput Geosci, 29:823. 2003.
92.
AugatP., MerkJ., GenantH., ClaesL.Quantitative assessment of experimental fracture repair by peripheral computed tomography. Calcif Tissue Int, 60:194. 1997.
93.
GrigoryanM., LynchJ., FierlingerA., GuermaziA., FanB., MacLeanD.et al.Quantitative and qualitative assessment of closed fracture healing using computed tomography and conventional radiography. Acad Radiol, 10:1267. 2003.
94.
StockS., BlackburnD., GradassiM., SimonH.Bone formation during forelimb regeneration: a microtomography (microCT) analysis. Dev Dyn, 226:410. 2003.
95.
CanceddaR., CedolaA., GiulianiA., KomlevV., LagomarsinoS., MastrogiacomoM.et al.Bulk and interface investigations of scaffolds and tissue-engineered bones by X-ray microtomography and X-ray microdiffraction. Biomaterials, 28:2505. 2007.
96.
KinneyJ.H., RyabyJ.T., HauptD.L., LaneN.E.Three-dimensional in vivo morphometry of trabecular bone in the OVX rat model of osteoporosis. Technol Health Care, 6:339. 1998.
97.
BayatS.A.L., BollerE., BrochardT., PeyrinF.In vivo imaging of bone micro-architecture in mice with 3D synchrotron radiation microtomography. Nucl Instr Meth A, 548:247. 2005.
98.
DavidV., LarocheN., BoudignonB., Lafage-ProustM.H., AlexandreC., RuegseggerP.et al.Noninvasive in vivo monitoring of bone architecture alterations in hindlimb-unloaded female rats using novel three-dimensional microcomputed tomography. J Bone Miner Res, 18:1622. 2003.
99.
BoydS.K., DavisonP., MullerR., GasserJ.A.Monitoring individual morphological changes over time in ovariectomized rats by in vivo micro-computed tomography. Bone, 39:854. 2006.
100.
BrunkeO.O.S., FritscheC., HilgerI., KaiserW.O.Determination of magnetic particle distribution in biomedical applications by X-ray microtomography. Journal of Magnetism and Magnetic Materials, 289:428. 2005.
101.
AlbertiniG., GiulianiA., KomlevV., MoronciniF., PugnaloniA., PennesiG.et al.Organization of extracellular matrix fibers within polyglycolic acid-polylactic acid scaffolds analyzed using X-ray synchrotron-radiation phase-contrast micro computed tomography. Tissue Eng Part C Methods, 15:403. 2009.
102.
TorrenteY., GavinaM., BelicchiM., FioriF., KomlevV., BresolinN.et al.High-resolution X-ray microtomography for three-dimensional visualization of human stem cell muscle homing. FEBS Lett, 580:5759. 2006.
103.
ChenW., MahmoodU., WeisslederR., TungC.Arthritis imaging using a near-infrared fluorescence folate-targeted probe. Arthritis Res Ther, 7:R310. 2005.
104.
CitrinD., LeeA., ScottT., SproullM., MénardC., TofilonP.et al.In vivo tumor imaging in mice with near-infrared labeled endostatin. Mol Cancer Ther, 3:481. 2004.
ZintchenkoA., SushaA., ConciaM., FeldmannJ., WagnerE., RogachA.et al.Drug nanocarriers labeled with near-infrared-emitting quantum dots (quantoplexes): imaging fast dynamics of distribution in living animals. Mol Ther, 17:1849. 2009.
107.
GuoH., YangJ., ShenoyN., MiaoY.Gallium-67-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide for primary and metastatic melanoma imaging. Bioconjug Chem, 20:2356. 2009.