Abstract
The Editors of Tissue Engineering: Part A retract the article entitled, “Cell Fate and Tissue Remodeling in Canine Urethral Repair Using a Bone Marrow Mesenchymal Stem Cell+Endothelial Progenitor Cell Amniotic Patch,” by Wenxin Zhang, Xin Zhang, Yihua Zhang, Xinke Zhang, Tong Zou, Wen Zhao, Yangou Lv, Jinglu Wang, Pengxiu Dai, Hao Cui, Yi Zhang, Dengke Gao, Chenmei Ruan, and Xia Zhang (epub ahead of print September 21, 2020; DOI: http://`.org/10.1089/ten.tea.2020.0129).
After the online publication of the article, the authors have indicated that they “feel that we have not yet studied our work completely and some new great results are discovered. So after carefully thinking, we are going to rearrange this manuscript and try to give more precise model. [sic]” The authors have not explained what those expected results will be, so it remains unclear the direction their work is headed.
The authors also indicated that they plan to submit an updated version of the paper to Tissue Engineering in the future. Upon submission the new manuscript will undergo rigorous peer review, and there is no guarantee of acceptance.
Impact statement
In the complete repair of a 3-cm-long circumferential urethral defect of the canine perineum using bone marrow mesenchymal stem cell (BMSC)+endothelial progenitor cell (EPC) amniotic membrane patch labeled with green and red fluorescent proteins, BMSCs mainly differentiated into urothelial cells, EPCs mainly differentiated into vascular endothelial cells, these two cells together participated in the repair of the urethral mucosal epithelium, and most of the submucosal tissues were formed by the growth of the adjacent recipient cells. Fluorescent protein labeling had no influence on stem cell proliferation and tissue repair ability.
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