Engineered Tissues as Customized Organ Germs

Nerem R.M. , and Sambanis A. Tissue engineering: from biology to biological substitutes. Tissue Eng, 1, 3, 1995.

Scotti C. , Tonnarelli B. , Papadimitropoulos A. , Scherberich A. , Schaeren S. , Schauerte A. , Lopez-Rios J. , Zeller R. , Barbero A. , and Martin I. Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering. Proc. Natl Acad Sci U S A, 104, 10476, 2010.

Scotti C. , Piccinini E. , Takizawa H. , Todorov A. , Bourgine P. , Papadimitropoulos A. , Barbero A. , Manz M.G. , and Martin I. Engineering of a functional bone organ through endochondral ossification. Proc. Natl Acad Sci U S A, 110, 3997, 2013.

Nakao K. , Morita R. , Saji Y. , Ishida K. , Tomita Y. , Ogawa M. , Saitoh M. , Tomooka Y. , and Tsuji T. The development of a bioengineered organ germ method. Nat Methods, 4, 227, 2007.

Ogawa M. , Oshima M. , Imamura A. , Sekine Y. , Ishida K. , Yamashita K. , Nakajima K. , Hirayama M. , Tachikawa T. , and Tsuji T. Functional salivary gland regeneration by transplantation of a bioengineered organ germ. Nat Commun, 4, 2498, 2013.

Sasai Y. , Eiraku M. , and Suga H. In vitro organogenesis in three dimensions: self-organising stem cells. Development, 139, 4111, 2012.

Lenas P. , Moos M. , and Luyten F.P. Developmental engineering: a new paradigm for the design and manufacturing of cell-based products. Part II: from genes to networks: tissue engineering from the viewpoint of systems biology and network science. Tissue Eng B, 15, 395, 2009.

Tonnarelli B. , Centola M. , Barbero A. , Zeller R. , and Martin I. Re-engineering development to instruct regeneration. Curr Top Dev Biol, 108, 319, 2014.

Bell E. Strategy for the selection of scaffolds for tissue engineering. Tissue Eng, 1, 163, 1995.

Lutolf M.P. , and Hubbell J.A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol, 23, 47, 2005.

Brown B.N. , and Badylak S.F. Extracellular matrix as an inductive scaffold for functional tissue reconstruction. Transl Res, 2013 [Epub ahead of print]; DOI: 10.1016/j.trsl.2013.11.003, 2013.

Bourgine P.E. , Pippenger B.E. , Todorov A. Jr. , Tchang L. , and Martin I. Tissue decellularization by activation of programmed cell death. Biomaterials, 34, 6099, 2013.

Loganathan R. , Potetz B.R. , Rongish B.J. , and Little C.D. Spatial anisotropies and temporal fluctuations in extracellular matrix network texture during early embryogenesis. PLoS One, 2012 [Epub ahead of print]; DOI: 10.1371/journal.pone.0038266.

Bourgine P.E. , Le Magnen C. , Pigeot S. , Geurts J. , Scherberich A. , and Martin I. Combination of immortalization and inducible death strategies to generate a human mesenchymal stromal cell line with controlled survival. Stem Cell Res, 2013 [Epub ahead of Print]; DOI: 10.1016/j.scr.2013.12.006