Is There a Current Role for Preoperative Non-Absorbable Oral Antimicrobial Agents for Prophylaxis of Infection after Colorectal Surgery?

Abstract

Abstract

Background:

In numerous scientific studies, oral antibiotic bowel preparation has reduced surgical site infections in patients undergoing colorectal surgery. The historical evolution of antibiotic bowel preparation is presented with a review of the scientific basis of its effectiveness.

Methods:

Review of the pertinent English language literature.

Results:

Successful oral antibiotic bowel preparation requires effective mechanical preparation. The progressive shift of preoperative preparation to the outpatient setting has led to a reduction in the use of oral antibiotics. Such preparation, however, continues to be effective although in current surgical practice is often augmented with perioperative, parenteral antimicrobials.

Conclusion:

Oral antibiotic bowel preparation has a role in the prevention of surgical site infection in the patient undergoing colorectal surgery.