2020 Alzheimer's disease facts and figures. Alzheimers Dement. 2020; 15:321–387.
2.
CsipoT, LipeczA, FulopGA, et al.Age-related decline in peripheral vascular health predicts cognitive impairment. Geroscience, 2019; 41:125–136.
3.
CsipoT, MukliP, LipeczA, et al.Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans. Geroscience, 2019; 41:495–509.
4.
LipeczA, CsipoT, TarantiniS, et al.Age-related impairment of neurovascular coupling responses: A dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults. Geroscience, 2019; 41:341–349.
5.
TarantiniS, Valcarcel-AresNM, YabluchanskiyA, et al.Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice. Aging Cell, 2018; 17:e12731.
6.
ParkL, AnratherJ, GirouardH, ZhouP, IadecolaC. Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain. J Cereb Blood Flow Metab, 2007; 27:1908–1918.
7.
NationDA, SweeneyMD, MontagneA, et al.Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction. Nat Med, 2019; 25:270–276.
8.
CsiszarA, YabluchanskiyA, UngvariA, Ungvari Z and TarantiniS. Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice. Geroscience, 2019; 41:609–617.
9.
UngvariZ, TarantiniS, Nyul-TothA, et al.Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: From increased cellular senescence to the pathogenesis of age-related vascular diseases. Geroscience, 2019; 41:727–738.
10.
WiedenhoeftT, TarantiniS, Nyul-TothA, et al.Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice. Geroscience, 2019; 41:711–725.
11.
TarantiniS, YabluchanskiyA, CsipoT, et al.Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging. Geroscience, 2019; 41:533–542.
12.
KissT, BalasubramanianP, Valcarcel-AresMN, et al.Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: A potential mechanism for the prevention of vascular cognitive impairment. Geroscience, 2019; 41:619–630.
13.
KissT, GilesCB, TarantiniS, et al.Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects. Geroscience, 2019; 41:419–439.
14.
TarantiniS, Valcarcel-AresMN, TothP, et al.Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol, 2019; 24:101192.
15.
Farias QuipildorGE, MaoK, HuZ, et al.Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice. Geroscience, 2019; 41:185–208.
16.
TothP, TarantiniS, AshpoleNM, et al.IGF-1 deficiency impairs neurovascular coupling in mice: Implications for cerebromicrovascular aging. Aging Cell, 2015; 14:1034–1044.
17.
FulopGA, AhireC, CsipoT, et al.Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice. Geroscience, 2019; 41:575–589.
