Abstract
As men age, serum testosterone concentrations fall, and they experience decreases in energy, bone mineral density, and muscle strength, which at least in part may be due to the fall in testosterone. Consequently, testosterone treatment has been considered for aging men. The possible benefits of testosterone treatment of aging men should be balanced, however, by its possible deleterious effects, including an increase in the prevalence of prostate cancer, benign prostatic hyperplasia, sleep apnea, lipid abnormalities, erythrocytosis, and hypercoagulability, all of which to some degree are testosterone dependent.
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