A 6-year-old girl presented with clinical signs of Cushing syndrome. Her medical history revealed that she had been treated with an unusual alternative therapy for atopic eczema and bronchial asthma.
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References
1.
ChisariA, SpinediE, VoirolMJ, GiovambattistaA, GaillardRC. A phospholipase A2-related snake venom (from Crotalus durissus terrificus) stimulates neuroendocrine and immune functions: determination of different sites of action. Endocrinology, 1998; 139:617–625.
2.
BalsindeJ, WinsteadMV, DennisEA. Phospholipase A(2) regulation of arachidonic acid mobilization. FEBS Lett, 2002; 531:2–6.
3.
KnepelW, MeyenG. Effect of various blockers of arachidonic acid metabolism on release of beta-endorphin- and adrenocorticotropin-like immunoreactivity induced by phospholipase A2 from rat adenohypophysis in vitro. Neuroendocrinology, 1986; 43:44–48.
4.
LeeAK, SmartJL, RubinsteinM, LowMJ, TseA. Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes. Endocrinology, 2011; 152:1901–1910.
5.
SpinediE, SalasM, ChisariA, PeroneM, CarinoM, GaillardRC. Sex differences in the hypothalamo-pituitary-adrenal axis response to inflammatory and neuroendocrine stressors. Evidence for a pituitary defect in the autoimmune disease-susceptible female Lewis rat. Neuroendocrinology, 1994; 60:609–617.
6.
MoreiraV, GutiérrezJM, SoaresAM, ZamunérSR, PurgattoE, Teixeira CdeF. Secretory phospholipases A(2) isolated from Bothrops asper and from Crotalus durissus terrificus snake venoms induce distinct mechanisms for biosynthesis of prostaglandins E2 and D2 and expression of cyclooxygenases. Toxicon, 2008; 52:428–439.
7.
BirtsCN, BartonCH, WiltonDC. Catalytic and non-catalytic functions of human IIA phospholipase A2. Trends Biochem Sci, 2010; 35:28–35.
8.
DahlR. Systemic side effects of inhaled corticosteroids in patients with asthma. Respir Med, 2006; 100:1307–1317.
9.
Wachstumskurven in Perzentilen. Friedrichsdorf, Germany: Milupa GmbH, 1997.
