Abstract
Since 1993, there have been several reports describing severe allergic reactions to gelatin. The initial report described a 17-year-old girl who experienced anaphylaxis to MMR vaccine. Subsequent reports followed describing anaphylactic reactions to other gelatin-containing vaccines and medications. This is the first case report of an allergic reaction to influenza vaccine due to gelatin allergy. Although, the incidence of anaphylaxis to gelatin is extremely low (about one case per 2 million doses), gelatin is the most common identifiable cause of severe allergic reaction to vaccines. A review of the literature and management of these patients is discussed.
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