Abstract
Drug hypersensitivity syndrome (DHS) is a potentially life-threatening form of drug reaction that is particularly associated with anticonvulsants. The role of glucocorticoids (GC) for treatment of this condition is controversial. We describe a child with DHS including severe cutaneous and hepatic involvement, which improved during GC treatment, flared when GC were inadvertently withdrawn, and resolved once they were again given. Our experience suggests GC may be of benefit to children with severe DHS. (Pediatr Asthma Allergy Immunol 2005; 18[3]:156–160.)
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