Abstract
The current literature suggests that more than 95% of males with cystic fibrosis (CF) are infertile, in contrast to approximately 50% of their female counterparts who may conceive. The present study examines patterns of fertility in a group of patients with CF based on clinical and laboratory studies performed over a longitudinal period of several years at the Georgetown University Cystic Fibrosis Clinic. Among the eight cases presented, four were female and four were male. Three women delivered three babies; two each delivered a live baby, a third a stillborn, and the fourth remained childless. Among the four men, one procreated one son, another patient two sons, and an additional two patients remain childless.
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