A Case of Bloom's Syndrome with Malignant Lymphoma

Abstract

We report a patient with Bloom's syndrome who developed diabetes mellitus at 21 years of age, which was complicated by a nasopharyngeal B-cell-type malignant lymphoma 9 months later. Although the tumor had been eradicated by radiation therapy, metastasis was detected in the cecum after 5 months. Chemotherapy could not be performed sufficiently due to bone marrow suppression, although powerful supportive care was provided. Hemicolectomy and radiation were also done but resulted in failure of remission. He died of abdominal bleeding at age 23 years and 9 months.