Abstract
A 10-year experience with children with systemic lupus erythematosus (SLE) at a university referral center is reported. Twenty SLE patients were followed for a mean of 6.75 years. The majority of these patients had clinical manifestations at presentation that remained dominant over their long-term course, the most frequent being arthritis, rash, and oral ulcerations. Forty percent developed clinical nephritis. The most common laboratory abnormalities were leukopenia, anemia, positive antinuclear antibody test, hypocomplementemia, and an elevated erythrocyte sedimentation rate (ESR). The overall prognosis was very good, with no mortality during this period of follow-up.
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