The Third Party Annotation (TPA) project collects and presents high-quality annotation of
nucleotide sequence. Annotation is submitted by researchers who have not themselves generated
novel nucleotide sequence. In its first few years, the resource has proven to be popular
with submitters from a range of biological research areas. Central to the project is the
requirement for high-quality data, resulting from experimental and inferred analysis discussed
in peer-reviewed publications. The data are divided into two tiers: those with experimental
evidence and those with inferential evidence. Standards for TPA are detailed and
illustrated with the aid of case studies.
This paper is part of the special issue of OMICS on data standards.
