TBIcare Investigators' Response to Papa and Wang (doi: 10:1089/neu.2017.5030): Raising the Bar for Traumatic Brain Injury Biomarker Research: Methods Make a Difference
Restricted accessLetterFirst published online May, 2019
TBIcare Investigators' Response to Papa and Wang (doi: 10:1089/neu.2017.5030): Raising the Bar for Traumatic Brain Injury Biomarker Research: Methods Make a Difference
PostiJ.P., HossainI., TakalaR.S., LiedesH., NewcombeV., OuttrimJ., KatilaA.J., FrantzénJ., Ala-SeppäläH., ColesJ.P., KyllönenA., MaanpääH.-R., TallusJ., HutchinsonP.J., Van GilsM., MenonD.K., and TenovuoO. (2017). Glial fibrillary acidic protein and ubiquitin C-terminal hydrolase-L1 are not specific biomarkers for mild CT-negative traumatic brain injury. J. Neurotrauma. E-pub ahead of print.
2.
PapaL., and WangK.K. (2017). Raising the bar for traumatic brain injury biomarker research: methods make a difference. J. Neurotrauma, 34, 2187–2189.
3.
PapaL., BrophyG., WelchR., LewisL., BragaC., TanC., AmeliN., LopezM., HaeusslerC., Mendez GiordanoD., SilvestriS., GiordanoP., WeberK., Hill-PryorC., and HackD. (2016). Time course and diagnostic accuracy of glial and neuronal blood biomarkers GFAP and UCH-L1 in a large cohort of trauma patients with and without mild traumatic brain injury. JAMA Neurol. 73, 551–560.
4.
WelchR., EllisM., LewisL., AyazS., MikaV., MillisS., and PapaL. (2017). Modeling the kinetics of serum glial fibrillary acidic protein, ubiquitin carboxyl-terminal hydrolase-L1, and S100B concentrations in patients with traumatic brain injury. J. Neurotrauma, 34, 1957–1971.
5.
The American Congress of Rehabilitation Medicine (ACRM). (1993). Definition of mild traumatic brain injury. J. Head Trauma Rehabil. 8, 86–87.
6.
KorleyF.K., Diaz-ArrastiaR., FalkH.J., PetersM.E., LeoutsakosJ.S., RoyD., RaoV., SairH.I., OfocheU., HallA.J., AkbariF., Van MeterT.E., EverettA.D., Van EykJ.E., and BechtoldK.T. (2017). Prevalence of incomplete functional and symptomatic recovery among patients with head injury but brain injury debatable. J. Neurotrauma, 34, 1531–1538.
7.
HondaM., TsurutaR., KanekoT., KasaokaS., YagiT., TodaniM., FujitaM., IzumiT., and MaekawaT. (2010). Serum glial fibrillary acidic protein is a highly specific biomarker for traumatic brain injury in humans compared with S-100B and neuron-specific enolase. J. Trauma, 69, 104–109.
8.
PapaL., AkinyiL., LiuM.C., PinedaJ.A., TepasJ.J.3rd, OliM.W., ZhengW., RobinsonG., RobicsekS.A., GabrielliA., HeatonS.C., HannayH.J., DemeryJ.A., BrophyG.M., LayonJ., RobertsonC.S., HayesR.L., and WangK.K. (2010). Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury. Crit. Care Med. 38, 138–144.
9.
MondelloS., LinnetA., BukiA., RobicsekS., GabrielliA., TepasJ., PapaL., BrophyG.M., TortellaF., HayesR.L., and WangK.K. (2012). Clinical utility of serum levels of ubiquitin C-terminal hydrolase as a biomarker for severe traumatic brain injury. Neurosurgery, 70, 666–675.
10.
PapaL., LewisL.M., FalkJ.L., ZhangZ., SilvestriS., GiordanoP., BrophyG.M., DemeryJ.A., DixitN.K., FergusonI., LiuM.C., MoJ., AkinyiL., SchmidK., MondelloS., RobertsonC.S., TortellaF.C., HayesR.L., and WangK.K. (2012). Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention. Ann. Emerg. Med. 59, 471–483.
11.
PapaL., LewisL.M., SilvestriS., FalkJ.L., GiordanoP., BrophyG.M., DemeryJ.A., LiuM.C., MoJ., AkinyiL., MondelloS., SchmidK., RobertsonC.S., TortellaF.C., HayesR.L., and WangK.K. (2012). Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial lesions and neurosurgical intervention. J. Trauma Acute Care Surg. 72, 1335–1344.
12.
PapaL., SilvestriS., BrophyG.M., GiordanoP., FalkJ.L., BragaC.F., TanC.N., AmeliN.J., DemeryJ.A., DixitN.K., MendesM.E., HayesR.L., WangK.K., and RobertsonC.S. (2014). GFAP out-performs S100beta in detecting traumatic intracranial lesions on computed tomography in trauma patients with mild traumatic brain injury and those with extracranial lesions. J. Neurotrauma, 31, 1815–1822.
13.
PuvennaV., BrennanC., ShawG., YangC., MarchiN., BazarianJ.J., Merchant-BornaK., and JanigroD. (2014). Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits. PLoS One, 9, e96296.
14.
KiviniemiA., GardbergM., FrantzénJ., ParkkolaR., VuorinenV., PesolaM., and MinnH. (2015). Serum levels of GFAP and EGFR in primary and recurrent high-grade gliomas: correlation to tumor volume, molecular markers, and progression-free survival. J. Neurooncol. 124, 237–245.
