KayT., HarringtonD.E., AdamsR., AndersonT., BerrolS., and CiceroneK. (1993). American Congress of Rehabilitative Medicine; definition of mild traumatic brain injury. J. Head Trauma Rehabil., 8, 86–87.
2.
PostiJ.P., HossainI., TakalaR.S., LiedesH., NewcombeV., OuttrimJ., KatilaA.J., FrantzenJ., Ala-SeppalaH., ColesJ.P., KyllonenA., MaanpaaH.R., TallusJ., HutchinsonP.J., van GilsM., MenonD.K., and TenovuoO. (2017). Glial fibrillary acidic protein and ubiquitin c-terminal hydrolase-l1 are not specific biomarkers for mild CT-negative traumatic brain injury. J. Neurotrauma. [Epub ahead of print.]
3.
PapaL., BrophyG.M., WelchR.D., LewisL.M., BragaC.F., TanC.N., AmeliN.J., LopezM.A., HaeusslerC.A., Mendez GiordanoD.I., SilvestriS., GiordanoP., WeberK.D., Hill-PryorC., and HackD.C. (2016). Time course and diagnostic accuracy of glial and neuronal blood biomarkers GFAP and UCH-L1 in a large cohort of trauma patients with and without mild traumatic brain injury. JAMA Neurol. 73, 551–560.
4.
PapaL., LewisL.M., FalkJ.L., ZhangZ., SilvestriS., GiordanoP., BrophyG.M., DemeryJ.A., DixitN.K., FergusonI., LiuM.C., MoJ., AkinyiL., SchmidK., MondelloS., RobertsonC.S., TortellaF.C., HayesR.L., and WangKK. (2012). Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention. Ann. Emerg. Med., 59, 471–483.
5.
PapaL., LewisL.M., SilvestriS., FalkJ.L., GiordanoP., BrophyG.M., DemeryJ.A., LiuM.C., MoJ., AkinyiL., MondelloS., SchmidK., RobertsonC.S., TortellaF.C., HayesR.L., and WangK.K. (2012). Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial lesions and neurosurgical intervention. J. Trauma Acute Care Surg., 72, 1335–1344.
6.
PapaL., SilvestriS., BrophyG.M., GiordanoP., FalkJ.L., BragaC.F., TanC.N., AmeliN.J., DemeryJ.A., DixitN.K., MendesM.E., HayesR.L., WangK.K., and RobertsonC.S. (2014). GFAP out-performs S100beta in detecting traumatic intracranial lesions on computed tomography in trauma patients with mild traumatic brain injury and those with extracranial lesions. J. Neurotrauma, 31, 1815–1822.
7.
JodoinM., RouleauD.M., Charlebois–PlanteC., BenoitB., LeducS., LaflammeG.Y., GosselinN., Larson–DupuisC., and De BeaumontL. (2016). Incidence rate of mild traumatic brain injury among patients who have suffered from an isolated limb fracture: upper limb fracture patients are more at risk. Injury, 47, 1835–1840.
8.
Diaz–ArrastiaR., WangK.K., PapaL., SoraniM.D., YueJ.K., PuccioA.M., McMahonP.J., InoueT., YuhE.L., LingsmaH.F., MaasA.I., ValadkaA.B., OkonkwoD.O., ManleyG.T., CaseyI.S., CheongM., CooperS.R., Dams–O'ConnorK., GordonW.A., HricikA.J., MenonD.K., MukherjeeP., SchnyerD.M., SinhaT.K., and VassarM.J. (2014) Acute biomarkers of traumatic brain injury: relationship between plasma levels of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein. J. Neurotrauma, 31, 19–25.
9.
WelchR.D., AyazS.I., LewisL.M., UndenJ., ChenJ.Y., MikaV.H., SavilleB., TyndallJ.A., NashM., BukiA., BarzoP., HackD., TortellaF.C., SchmidK., HayesR.L., VossoughA., SweridukS.T., and BazarianJ.J. (2016). Ability of serum glial fibrillary acidic protein, ubiquitin C-terminal hydrolase-L1, and S100B to differentiate normal and abnormal head computed tomography findings in patients with suspected mild or moderate traumatic brain injury. J. Neurotrauma, 33, 203–214.
10.
LewisL.M., SchloemannD., PapaL., FucetolaR., BazarianJ., LindburgM., and WelchR. (2017). Utility of serum biomarkers in the diagnosis and stratification of mild traumatic brain injury. Acad. Emerg. Med. [Epub ahead of print].
11.
ButtonK.S., IoannidisJ.P., MokryszC., NosekB.A., FlintJ., RobinsonE.S., and MunafoM.R. (2013). Power failure: why small sample size undermines the reliability of neuroscience. Nat. Rev. Neurosci., 14, 365–376.
12.
MullerK., ElverlandA., RomnerB., WaterlooK., LangbakkB., UndenJ., and IngebrigtsenT. (2006). Analysis of protein S-100B in serum: a methodological study. Clin. Chem. Lab. Med., 44, 1111–1114.
13.
PostiJ.P., TakalaR.S., RunttiH., NewcombeV.F., OuttrimJ., KatilaA.J., FrantzenJ., Ala-SeppalaH., ColesJ.P., HossainM.I., KyllonenA., MaanpaaH.R., TallusJ., HutchinsonP.J., vanGils, M., MenonD.K., and TenovuoO. (2016). The levels of glial fibrillary acidic protein and ubiquitin C-terminal hydrolase-L1 during the first week after a traumatic brain injury: correlations with clinical and imaging findings. Neurosurgery, 79, 456–464.
14.
LoveS.A., SandovalY., SmithS.W., NicholsonJ., CaoJ., LerR., SchulzK., and AppleF.S. (2016). Incidence of undetectable, measurable, and increased cardiac troponin i concentrations above the 99th percentile using a high-sensitivity vs a contemporary assay in patients presenting to the emergency department. Clin. Chem., 62, 1115–1119.
15.
SofroniewM.V., and VintersH.V. (2010). Astrocytes: biology and pathology. Acta Neuropathol. 119, 7–35.
16.
BishopP., RoccaD., and HenleyJ.M. (2016). Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction. Biochem. J., 473, 2453–2462.