An Optimum Animal Model for Neonatal Thoracoscopy

Abstract

Abstract

Purpose:

This study attempted to define an optimum animal model for neonatal thoracoscopy.

Materials and Methods:

Seven rabbits and three 5–7-kg piglets were subjected to thoracoscopy by three pediatric surgeons. The outcome for the successful completion of esophageal anastomosis and additional procedures, including diaphragmatic plication and lung biopsy, were noted.

Results:

Whereas esophageal anastomosis could be accomplished in all piglets, it could be achieved in only 1 rabbit. Additional procedures were possible in 2 piglets and no rabbits. Anesthetic complications were seen in 4 rabbits and 1 piglet.

Conclusion:

Our findings suggest that the piglet may be the optimum animal model for replicating neonatal thoracoscopy. The fragility of the rabbit, coupled with a limited intrathoracic working space, limits its use for thoracoscopy.