Abstract
Background:
This study investigates how lifestyle factors and westernization contribute to obesity and examines the influence of body mass index (BMI) changes and lifestyle factors on “lipitension,” a significant risk factor for heart disease and metabolic syndrome.
Methods:
This prospective study focused on women aged 20–64 without pre-existing hypertension and dyslipidemia who underwent regular medical checkups between April 2016 and March 2022. Anthropometric measurements and blood pressure, along with low-density lipoprotein, high-density lipoprotein, and triglycerides levels, were assessed.
Results:
Over an average 46.5-month follow-up, 11.5% of initially healthy young and middle-aged women developed lipitension. Categorizing participants based on BMI changes revealed stable (63.8%), decreased (12.5%), and increased (23.8%) groups within this 11.5%. Increased BMI is linked with a heightened hazard risk for lipitension. Women with increased BMI who refrained from snacking (aHR [95% confidence interval (CI)] = 2.750 [1.433–5.279]), avoided late-night eating (aHR [95% CI] = 1.346 [1.032–1.754]), and engaged in alcohol consumption (aHR [95% CI] = 2.037 [1.138–3.646]) showed an elevated risk. Conversely, within the decreased BMI group, behaviors like skipping breakfast (aHR [95% CI] = 0.190 [0.047–0.764]), eating quickly (aHR [95% CI] = 0.457 [0.215–0.972]), and not eating late (aHR [95% CI] = 0.665 [0.467–0.948]) were associated to a reduced lipitension. Subgroup analysis for women with BMI <23 revealed specific behaviors influencing lipitension risk in both BMI-increased and BMI-stable groups.
Conclusion:
Customized interventions, including for women with BMI <23, enhance heart health, mitigating global lifestyle diseases and obesity.
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