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Abstract

Background:

Limited data are available on hepatitis rates during pregnancy by socio-demographic characteristics. This study examined temporal trends in hepatitis B virus (HBV) and hepatitis C virus (HCV) mono-infections and HIV/HBV and HIV/HCV co-infections in subpopulations among pregnant women in Florida between 1998 and 2007.

Methods:

We analyzed all Florida live births from 1998 to 2007 using hospital discharge data linked to birth records.

Results:

The total sample size was 1,700,734 singleton live births. The prevalence of HBV in pregnancy rose from 65.4 per 100,000 births to 123.5 per 100,000 births (p<0.0001 for trend), and the prevalence of HCV in pregnancy increased from 17.0 per 100,000 births to 125.1 per 100,000 births (p<0.0001 for trend). Compared with white mothers, black mothers were more than twice as likely to have HBV in pregnancy (adjusted rate ratios [ARR]=2.24; 95% CI=1.97–2.53). Black mothers were 69% (ARR=0.31, 95% CI=0.25–0.39) and Hispanic mothers were 51% (ARR=0.49, 95% CI=0.41–0.60) less likely to have HCV compared with white mothers.

Conclusions:

Although the overall prevalence rate of HBV increased over the past decade, black women still had a noticeably higher rate of infection. Similarly, white women and those with HIV co-infection had noticeably higher rates of HCV infection over the study period. Our findings call for improved and increased HBV/HCV prevention, screening, and immunization programs among minority women of childbearing age.

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Prevalence and Temporal Trends of Hepatitis B,Hepatitis C,and HIV/AIDS Co-infection During Pregnancy Across the Decade,1998–2007

Abstract

Background:

Methods:

Results:

Conclusions:

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